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Bayesian Analysis of Multiway Tables in Association Studies: A Model Comparison Approach
Bayesian Analysis Multiway Tables Association Studies Model Comparison Approach
2012/9/17
We consider the problem of statistical inference on unknown quantities structured as a multiway table. We show that such multiway tables are naturally formed by arranging regression coecients in comp...
Simultaneous Model Selection and Estimation for Mean and Association Structures with Clustered Binary Data
association clustered binary data generalized estimating equation logistic regression variable selection
2012/9/17
This paper investigates the property of the penalized estimating equations when both the mean and association structures are modelled. To select variables for the mean and association structures seque...
Integrated analysis of variants and pathways in genome-wide association studies using polygenic models of disease
Integrated analysis of variants pathways genome-wide association studies polygenic models of disease
2012/9/18
Many common diseases are highly polygenic, modulated by a large number genetic factors with small effects on suscep-tibility to disease. These small effects are difficult to map reliably in genetic as...
Simultaneous SNP identification in association studies with missing data
Hierarchical models Bayes models Gibbs sampling genome-wide association.
2012/9/18
Association testing aims to discover the underlying relationship between genotypes (usually Single Nucleotide Polymorphisms, or SNPs) and phenotypes(attributes, or traits). The typically large data se...