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2022年4月12日,病原生物学研究所郭斐团队在Science Signaling发表了题为“SARS-CoV-2 spike protein–induced cell fusion activates the cGAS-STING pathway and the interferon response”的文章,阐述SARS-CoV-2 virus诱导的细胞-细胞融合对于I型干扰素应答的影响,被选...
CAN RECONSTRUCTED LAND SURFACE TEMPERATURE DATA FROM SPACE PREDICT A WEST NILE VIRUS OUTBREAK?
West Nile Virus outbreaks Greece Land Surface Temperature MODIS GRASS GIS Time series analysis
2017/8/10
Temperature is one of the main drivers of ecological processes. The availability of temporally and spatially continuous temperature time series is crucial in different research and application fields,...
Inhibitory Effect of Gamma Irradiation against Cucumber Green Mottle Mosaic Virus
coat protein ionising radiation virus inactivation virion
2018/3/5
Gamma irradiation has been shown to be an effective method of controlling plant bacterial and fungal pathogens, but
data on its effect against plant viruses is limited. A mechanism for the inactivati...
A Procedure for Estimating the Unconditional Cumulative Incidence Curve and Its Variability for the Human Immunodeficiency Virus
Confidence intervals for cumulative human immunodeficiency virus incidence curve Human immunodeficiency virus incidenc
2015/7/31
A backcalculation procedure is presented for estimating both the cumulative incidence of the
human immunodeficiency virus (HIV)-the total number of seropositive individuals as a function
of calend...
Obstacles and Circumvention Strategies for Hematopoietic Stem Cell Transduction by Recombinant Adeno-associated Virus Vectors
gene therapy hematopoietic stem cells sickle cell disease
2015/5/21
High-efficiency transduction of hematopoietic stem cells (HSCs) by recombinant adeno-associated virus serotype 2 (AAV2) vectors is limited by (i) inadequate expression of cellular receptor/co-receptor...
RNA-dependent RNA polymerase of turnip crinkle virus and the effect of coat protein on the replication of subviral RNAs
Biological sciences
2015/1/28
In this dissertation, I report the functions of the TCV coat protein in TCV viral and subviral RNA replication using in vivo and in vitro systems. In chapter 2, I present my results on construction of...
Characterization of a novel baculovirus, gonad-specific virus, GSV
Biological sciences insect sterility Helicoverpa zea
2015/1/28
A newly discovered, nonoccluded baculovirus GSV has been reported to be a causative agent of sterility in adult corn ear-worms, Helicoverpa zea. Previous studies conducted by Hamm et al. (1996) and ou...
Difference in reactions of apricot and peach cultivars to Plum pox virus: serological and symptomatological evaluation
ELISA resistance susceptibility
2015/1/20
Differences in reactions to infection and different development of Plum pox virus (PPV) symptoms were observed in leaves and fruits of one hundred sixty-five apricot and seventy-nine peach cultivars a...
The development and application of an indirect Elisa test for the detection of antibodies to bovine respiratory syncytial virus in blood serum
bovine respiratory syncytial virus (BRSV) respiratory tract pathogen cattle ELISA
2015/1/20
We developed an indirect enzyme-linked immunosorbent assay (ELISA) for detection of serum antibodies to bovine respiratory syncytial virus. For evaluation of the newly developed ELISA, field sera coll...
Symptom modulation by subviral RNAs associated with turnip crinkle virus
Plants the virus the virus symptoms radish knit virus satellite RNA and toxicity
2014/12/11
Many plant RNA viruses provide replication and encapsidation functions for one or more subviral RNAs that can modulate the symptoms of the associated helper virus. In this dissertation, I report my st...
Replication and 3'-end repair of a subviral RNA associated with turnip crinkle virus
RNA virus satellite RNA radish virus
2014/12/11
Replication of plus (+)-strand RNA viruses proceeds through minus (−)-strand intermediates. Satellite RNA C (satC), one of the nonessential subviral RNAs of Turnip crinkle virus (TCV), is depend...
Allosteric Regulation of Dengue Virus Type 2 Protease
Dengue Virus Structure of NS2B-NS3pro
2014/11/20
Dengue Fever is a global problem with a worldwide effectiveness that put 2.5 Billion people under the risk, infect 50 million people and causes 30000-50000 people death each year. DHF was first recogn...
Effect of artificial dsRNA on infection of pea plants by Pea seed-borne mosaic virus
isum sativum PSbMV RNA vaccine qRT-PCR
2014/7/9
The effect of direct application of artificial dsRNA molecules derived from the viral coat protein gene and the possibility of RNA interference induction leading to protection against Pea seed borne m...
Genetic variability of the Czech Pea enation mosaic virus isolates
coat protein PEMV-1 PEMV-2 phylogenetic analysis satellite RNA
2014/7/9
The Pea enation mosaic virus is an example of symbiogenesis of taxonomically unrelated PEMV-1 and PEMV-2 viruses. Partial RNA sequences, PEMV-1 coat protein, PEMV-2 movement protein gene and satellite...
Characterization of Hepatitis C Virus Infection of Hepatocytes and Astrocytes
exosome IL-18, 3D live cell imaging
2015/5/21
Approximately 2.8% of the world population is currently infected with hepatitis C virus (HCV). Neutralizing antibodies (nAbs) are often generated in chronic hepatitis C patients yet fail to control th...