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Development and evaluation of a hydrogenated rosin (β-acryloxyl ethyl) ester–bonded silica stationary phase for high-performance liquid chromatography separation of paclitaxel from yew bark
Rosin-based stationary phase Paclitaxel Retention mechanism Separation Yew-bark extract
2023/12/5
Paclitaxel (PTX) is a complex diterpenoid anticancer drug whose separation from yew biomass poses a significant challenge. In this study, a new stationary phase comprising hydrogenated rosin (β-acrylo...
Paclitaxel alters the function of the small diameter sensory neurons
Small diameter sensory neurons paclitaxel vasodilatation
2015/5/21
Although paclitaxel is a commonly used anti-neoplastic agent for the treatment of solid tumors, therapy often results in a number of side effects, the most debilitating of which is peripheral neuropat...
Novel Systems for the Functional Characterization of Genes Related to Paclitaxel Metabolism in Taxus Cell Cultures
agrobacterium cell culture paclitaxel
2015/1/5
Human society has benefited greatly from plant secondary metabolites, often utilizing a variety of compounds as dyes, food additives, and drugs. In particular, pharmaceutical development has benefited...
Clinical Experience regarding Paclitaxel Treatment for Scalp Angiosarcomas: A Preliminary Report
Scalp Angiosarcoma Paclitaxel Radiotherapy
2009/7/15
Background: Scalp angiosarcoma is an aggressive tumor characterized by a rapid and fatal course. The overall prognosis of scalp angiosarcomas is poor. Recently, paclitaxel was found to be useful for s...
The Effects of Benzo(A) Pyrene Doxorubicin and Paclitaxel on P170 Glycoprotein
benzo(a)pyrene doxorubicin paclitaxel p170 glycoprotein rat
2009/6/29
B(a)P is a mutagenic, carcinogenic and teratogenic substance. Paclitaxel and doxorubicin are antineoplastic drugs widely used in cancer treatment. The purpose of this study is to observe the effects o...