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A National Security Enterprise Response - Digital Dimension Disruption
Security Enterprise Response Digital Dimension Disruption The Informatized Era
2019/10/22
The digital dimension is simultaneously enhancing and disrupting the fabric of life in every society where modern, informatized technology is present.1 The slow-motion collapse of parts of the 20th ce...
Numerical simulations of collisional disruption of rotating gravitational aggregates:Dependence on material properties
Asteroids Planetesimals Dynamics N-body simulations Collisional physics
2015/12/25
Our knowledge of the strengths of small bodies in the Solar System is limited by our poor understanding of their internal structures, and this, in turn, clouds our understanding of the formation and e...
Selective sampling during catastrophic disruption:Mapping the location of reaccumulated fragments in the original parent body
Asteroids Collisions Internal structure Gravitational reaccumulations
2015/12/25
In this paper, we simulate numerically the catastrophic disruption of a large asteroid as a result of a collision with a smaller projectile and the subsequent reaccumulation of fragments as a result o...
ROTATION-DEPENDENT CATASTROPHIC DISRUPTION OF GRAVITATIONAL AGGREGATES
minor planets asteroids:general planets and satellites:formation planets and satellites:physical evolution
2015/12/25
We carry out a systematic exploration of the effect of pre-impact rotation on the outcomes of low-speed collisions between planetesimals modeled as gravitational aggregates. We use pkdgrav, a cosmolog...
Spin-up of rubble-pile asteroids:Disruption,satellite formation,and equilibrium shapes
Asteroid, Dynamics Rotational dynamics Satellites,Dynamics
2015/12/25
We present results from numerical experiments testing the behavior of cohesionless gravitational aggregates experiencing a gradual increase of angular momentum. The test bodies used in these numerical...
Asteroids are leftover pieces from the era of planet formation that help us understand conditions in the early Solar System. Unlike larger planetary bodies that were subject to global thermalmodificat...
Fragment properties at the catastrophic disruption threshold:The effect of the parent body’s internal structure
Asteroids Collisional physics Asteroids, Composition
2015/12/25
Numerical simulations of asteroid breakups, including both the fragmentation of the parent body and the gravitational interactions between the fragments, have allowed us to reproduce successfully the ...
A steady-state model of NEA binaries formed by tidal disruption of gravitational aggregates
Asteroids dynamics Satellites of asteroids
2015/12/25
We present results of a simulation of a steady-state binary near-Earth asteroid (NEA) population. This study combines previous work on tidal disruption of gravitational aggregates [Walsh, K.J., Richar...
Catastrophic disruption of asteroids and family formation:a review of numerical simulations including both fragmentation and gravitational reaccumulations
Asteroids composition Asteroids dynamics Collisional physics Impact processes
2015/12/25
In the last few years, thanks to the development of sophisticated numerical codes, a major breakthrough has been achieved in our understanding of the processes involved in small bodycollisions. In thi...
Catastrophic disruption of pre-shattered parent bodies
Asteroids composition Asteroids dynamics Collisional physics Impact processes
2015/12/25
In this paper, we analyze the effect of the internal structure of a parent body on its fragment properties following its disruption in different impact energy regimes. To simulate an asteroid breakup,...
Formation of Asteroid Families by Catastrophic Disruption:Simulations with Fragmentation and Gravitational Reaccumulation
asteroids dynamics planetesimals resonances surfaces asteroids
2015/12/25
This paper builds on preliminary work in which numerical simulations of the collisional disruption of large asteroids (represented by the Eunomia and Koronis family parent bodies) were performed and w...
Cyclooxygenase Inhibition Limits Blood-Brain Barrier Disruption following Intracerebral Injection of Tumor Necrosis Factor-alpha in the Rat
cyclooxygenase-2 COX-2 COX-1 prostaglandin E2 neuroinflammation blood-brain barrier ischemia stroke matrix metalloproteinase MMP-3 MMP-9 gelatinase B stromelysin-1 oxidative stress indomethacin cyclooxygenase-1 glutathione free radicals MRI
2015/7/29
Increased permeability of the blood-brain barrier (BBB) is important in neurological disorders. Neuroinflammation is associated with increased BBB breakdown and brain injury. Tumor necrosis factor-alp...
Barrier disruption in STAT6VT transgenic mice as a potential model for atopic dermatitis skin inflammation
STAT6VT transgenic Atopic Dermatitis
2015/5/25
Atopic dermatitis (AD) is a pruritic, chronic inflammatory skin disease with a lifetime prevalence of 10-20% in children and 1-3% in adults, worldwide. In the past three decades, prevalence of the dis...
The dynamics of satellite disruption in cold dark matter haloes
numerical N-body simulation
2014/12/22
We investigate the physical mechanisms of tidal heating and satellite disruption in cold dark matter host haloes using N-body simulations based on cosmological initial conditions. We show the importan...
Genome-wide analysis for native thyroid hormone targets in developing brain and mechanisms of endocrine disruption at the thyroid hormone receptor
Thyroid hormone fetal brain development interference and signal brain development polychlorinated biphenyls (PCBS)
2014/12/11
Thyroid hormone (TH) plays an important role in fetal brain development. Therefore, exogenous factors that interfere with TH signaling may exert potentially important adverse effects on brain developm...
