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SBA-term: Sparse Bilingual Association for Terms
SBA-term Sparse Bilingual Association Terms
2016/1/19
Bilingual semantic term association is very use-ful in cross-language information retrieval, statistical machine translation, and many other applications in natural language processing. In this paper,...
A Penalized Multi-trait Mixed Model for Association Mapping in Pedigree-based GWAS
Multivariate linear mixed model Penalization approach Feature selection 1 arXiv:1305.4413v1 [stat.ME] 19 May 2013 GWAS
2013/6/14
In genome-wide association studies (GWAS), penalization is an important approach for identifying genetic markers associated with trait while mixed model is successful in accounting for a complicated d...
Efficient Algorithms for Multivariate Linear Mixed Models in Genome-wide Association Studies
Efficient Algorithms Multivariate Linear Mixed Models Genome-wide Association Studies
2013/6/17
Multivariate linear mixed models (mvLMMs) have been widely used in many areas of genetics, and have attracted considerable recent interest in genome-wide association studies (GWASs). However, existing...
The vast majority of connections between complex disease and common genetic variants were identified through meta-analysis, a powerful approach that enables large samples sizes while protecting agains...
A Distance-Based Test of Association Between Paired Heterogeneous Genomic Data
A Distance-Based Test Association Between Paired Heterogeneous Genomic Data
2013/4/28
Due to rapid technological advances, a wide range of different measurements can be obtained from a given biological sample including single nucleotide polymorphisms, copy number variation, gene expres...
Replicability analysis for Genome-wide Association studies
Replicability analysis Genome-wide Association studies
2012/11/22
The paramount importance of replicating associations is well recognized in the genome-wide associaton (GWA) research community, yet methods for assessing replicability of associations are scarce. Publ...
Bayesian Analysis of Multiway Tables in Association Studies: A Model Comparison Approach
Bayesian Analysis Multiway Tables Association Studies Model Comparison Approach
2012/9/17
We consider the problem of statistical inference on unknown quantities structured as a multiway table. We show that such multiway tables are naturally formed by arranging regression coecients in comp...
Simultaneous Model Selection and Estimation for Mean and Association Structures with Clustered Binary Data
association clustered binary data generalized estimating equation logistic regression variable selection
2012/9/17
This paper investigates the property of the penalized estimating equations when both the mean and association structures are modelled. To select variables for the mean and association structures seque...
Integrated analysis of variants and pathways in genome-wide association studies using polygenic models of disease
Integrated analysis of variants pathways genome-wide association studies polygenic models of disease
2012/9/18
Many common diseases are highly polygenic, modulated by a large number genetic factors with small effects on suscep-tibility to disease. These small effects are difficult to map reliably in genetic as...
Simultaneous SNP identification in association studies with missing data
Hierarchical models Bayes models Gibbs sampling genome-wide association.
2012/9/18
Association testing aims to discover the underlying relationship between genotypes (usually Single Nucleotide Polymorphisms, or SNPs) and phenotypes(attributes, or traits). The typically large data se...
Association Marocaine Planification Familiale: Effective participation of youth
Women's health Planification Familiale
2014/3/28
This case study is one of a series of qualitative reviews called “IPPF Changing lives” which capture the stories of IPPF’s beneficiaries and clients from around the world. A rapid PEER (participatory ...
Bayesian Sparsity-Path-Analysis of Genetic Association Signal using Generalized t Priors
Bayesian Sparsity-Path-Analysis Genetic Association Signal
2011/7/5
We explore the use of generalized t priors on regression coefficients to help understand the nature of association signal within "hit regions" of genome-wide association studies.
A model selection approach to genome wide association studies
Genome wide association Multiple testing Linear regression,
2010/10/14
For the vast majority of genome wide association studies (GWAS) published so far, statistical analysis was performed by testing markers individually. In this article we present some elementary statis...
Does adjustment for measurement error induce positive bias if there is no true association?
adjustment measurement error positive bias true association
2010/3/18
This article is a response to an off-the-record discussion that I had at an international meeting of epidemiologists. It centered on a concern, perhaps widely spread, that measurement error
adjustmen...
Association Discrimination Under the Americans with Disabilities Act: Another Uphill Battle for Potential ADA Plaintiffs
Disabilities Act Potential ADA Plaintiffs
2009/11/13
In 1990, President George H. Bush signed the Americans with Disabilities
Act (“ADA”)1 into law.2 At the signing of this Act, he praised it
as being a “landmark” piece of legislation that would enabl...