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痛风是一种以嘌呤代谢障碍，高尿酸血症为基础，导致关节和肾脏等全身多系统受累的炎症性免疫疾病。痛风性关节炎的特征是单钠尿酸盐结晶在关节内和关节周围沉积，急性发作时可引起关节局部红、肿、热、痛，影响全世界约6~10亿人。随着物质生活水平的提高，我国截至目前高尿酸血症患者约有1.4亿人，痛风患者超过1000万人。痛风除了影响关节以外，也与慢性肾病、心血管疾病、脑血管疾病和性功能障碍发生有关。痛风治疗的关...
Personalized Learning in an Online Drugs and US Health Care System Controversies Course
Personalized Learning Online Drugs
2018/11/22
Objective. To examine if personalized learning objectives influenced student engagement and if achievement of objectives could be measured from course assignments.
Methods. Learners created personali...
Use of an Online Spaced-Education Game to Study Top 200 Drugs in a Skills Laboratory Course
Use Online Spaced-Education Game
2018/11/22
Objective. To describe the use of an online spaced-education (SE) game to study top 200 drug information in a first-year skills laboratory course.
Methods. There were 236 students enrolled in a volun...
The role of statin drugs in combating cardiovascular diseases–A review
Cardiovascular disease Hyperlipidaemic patients statin drugs
2015/7/21
Statins clearly confer substantial benefit in people with established cardiovascular (CV) disease. Increased cholesterol levels have been associated with cardiovascular diseases (CVD), and statins are...
EVALUATION OF GENE REGULATION AND THERAPEUTIC DRUGS RELATED TO ALZHEIMER’S DISEASE IN DEGENERATING PRIMARY CEREBROCORTICAL CULTURES
Alzheimer synapse neurodegeneration primary culture memantine
2015/5/21
Alzheimer’s disease (AD) is a neurological disorder defined by the presence of plaques comprised mostly of amyloid-β (Aβ), and neurofibrillary tangles consisting of hyperphosphorylated microtubule ass...
Sarcomas are a rare group of malignant mesenchymal tumours arising from bone and soft tissue. The diversity of this group of tumours and the rarity of each subtype poses significant challenges in the ...
Developing and Implementing Guidelines for the Safe Handling of Cytotoxic Drugs and Related Waste: The Queensland Experience
Developing and Implementing Guidelines the Safe Handling Cytotoxic Drugs Related Waste The Queensland Experience
2015/3/9
A greater understanding of the nature of cancer and the role of cytotoxic drugs in treating malignant and non-malignant disease has led to an increase use of chemotherapy in a variety of clinical and ...
Types of Nasal Delivery Drugs and Medications in Iranian Traditional Medicine to Treatment of Headache
Headache Herbal Medicine Nose Analgesics
2015/10/13
Context:: Headache is a common symptom throughout the world. The main purpose of patient-centered approaches is the utilization of useful and simple treatment. Nowadays, there is a rising propensity t...
Prevention of Intraabdominal Adhesions by Local and Systemic Administration of Immunosuppressive Drugs
Pharmaceutical Preparations Immunosuppression Peritoneum General Surgery
2015/10/9
Background: Intraperitoneal adhesion formation is a serious postsurgical issue. Adhesions develop after damage to the peritoneum by surgery, irradiation, infection or trauma.
New antimyeloma drugs in spinal cord infiltration for multiple myeloma. Determination of lenalidomide in cerebrospinal fluid with ultrasensitive high-performance liquid chromatography
Lenalidomide Multiple Myeloma Spinal Cord Infiltration
2013/1/30
A 64-year-old woman with IgA kappa multiple myeloma was treated with thalidomide-dexa- methasone. Due to progression of the disease, bortezomib, doxorubicin and dexamethasone were administered, follow...
《Formulating Poorly Water Soluble Drugs》（图）
Formulating Poorly Water Soluble Drugs Robert O. Williams III, Alan B. Watts Dave A. Miller
2013/12/4
This volume is intended to provide the reader with a breadth of understanding regarding the many challenges faced with the formulation of poorly water-soluble drugs as well as in-depth knowledge in th...
Teaching the Pharmacology of Antiarrhythmic Drugs
arrhythmia antiarrhythmic agents pharmacology integrated curriculum
2018/5/31
Objective. To provide doctor of pharmacy (PharmD) students with highly integrated, comprehensive and up-to-date instruction related to the pharmacology of antiarrhythmic drugs.
Design. Students were ...
In vitro effects of some drugs on human erythrocyte glutathione reductase
Glutathione reductase dacarbazine thiocolchicoside methotrexate
2011/3/22
The effects of dacarbazine, thiocolchicoside, methotrexate, olanzapine, pantoprazole sodium, and 5-fluorouracil on the enzyme activity of glutathione reductase (GR) were studied using human erythrocyt...
In vitro effect of current antimalarial drugs on the survival of paired Schistosoma mansoni adult worms and their egg production
antischistosomal drugs antimalarial drugs Schistosoma mansoni
2010/12/10
Some field trials have already demonstrated the high antischistosomal potential of combination therapies using Artesunate (ART) and current antimalarial drugs (Boulanger et al., 2007; Mohamed et al., ...
Modeling the electrophoretic mobility of basic drugs in aqueous-Methanolic buffers in capillary electrophoresis
Beta-blockers Water-methanol mixture capillary electrophoresis
2010/1/6
The electrophoretic mobility of three beta-blocker drugs, i.e. nadolol, oxprenolol and pindolol, in sodium acetate buffer containing different concentrations of methanol varying from 0 to 100 percent ...
