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RNA nanoparticle therapy stops the spread of incurable bone marrow cancer（图）
RNA 纳米颗粒疗法 骨髓癌 肿瘤治疗
2023/6/27
Multiple myeloma is an incurable bone marrow cancer that kills over 100,000 people every year. Known for its quick and deadly spread, this disease is one of the most challenging to address. As these c...
Data suggests stopping immunotherapy after two years is reasonable in patients with advanced lung cancer（图）
晚期肺癌 免疫治疗 停止治疗
2023/6/27
Over the past decade, the approval of immune checkpoint inhibitors has revolutionized treatment for patients with advanced lung cancer, helping many live longer lives and improving overall survival fo...
In the five years since the FDA’s initial approval of chimeric antigen receptor (CAR) T cell therapy, Penn Medicine has gleaned 20 additional approvals related to drugs and techniques to treat or dete...
Every three to five days, all of the cells lining the human intestine are replaced. That constant replenishment of cells helps the intestinal lining withstand the damage caused by food passing through...
In what may turn out to be a long-missing piece in the puzzle of breast cancer, Harvard Medical School researchers have identified the molecular sparkplug that ignites cases of the disease currently u...
A novel cancer therapeutic, combining antibody fragments with molecularly engineered nanoparticles, permanently eradicated gastric cancer in treated mice, a multi-institutional team of researchers fou...
Immunotherapy — drug treatment that stimulates the immune system to attack tumors — works well against some types of cancer, but it has shown mixed success against lung cancer.
Treating cancer with combinations of drugs can be more effective than using a single drug. However, figuring out the optimal combination of drugs, and making sure that all of the drugs reach the right...
Cancer is characterized by a number of key biological processes known as the “hallmarks of cancer,” which remodel cells and their immediate environment so that tumors can form, grow, and thrive. Many ...
A portable diagnostic device designed by researchers at Cornell Engineering and Weill Cornell Medicine has been deployed in clinical tests in Uganda to identify cases of Kaposi sarcoma, a common yet d...
Cancer cells selectively load ‘drones’ to keep T cells from infiltrating tumors（图）
癌细胞 选择性加载 T细胞 浸润肿瘤
2023/7/7
Checkpoint inhibitor drugs have been a gamechanger for many cancer patients. Yet around 70% don’t respond to these medications, which work by removing the “brakes” on the immune system’s response to a...
NGAOUNDERE AND YAOUNDE, CAMEROON – When Bobbo Hamadou gets up in the morning, he opens the door and window in his house. This is not just to air out his mattress – but to lower the concentration of ra...
近日，中南大学生命科学学院夏赞贤教授团队在国际学术期刊Molecular Cancer （IF=27.4）发表了题为“M6A-mediated upregulation of circMDK promotes tumorigenesis and acts as a nanotherapeutic target in hepatocellular carcinoma“的研究论文，首次发现circMD...
Over time, cancer cells can evolve to become resistant to treatment, more aggressive, and metastatic — capable of spreading to additional sites in the body and forming new tumors. The more of these tr...
Method for delivering immune system-stimulating drugs may enhance cancer immunotherapy（图）
递送 免疫系统 刺激药物 癌症免疫治疗
2023/6/7
Stimulating the body’s immune system to attack tumors is a promising way to treat cancer. Scientists are working on two complementary strategies to achieve that: taking off the brakes that tumors put ...