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Study finds a new way to shut down cancer cells’ ability to consume glucose（图）
shut down cancer cells ability to consume glucose
2017/11/23
Cancer cells consume exorbitant amounts of glucose, a key source of energy, and shutting down this glucose consumption has long been considered a logical therapeutic strategy. However, good pharmacolo...
P53 “master switch” remains top target in gene signaling network controlling cancer suppression（图）
P53 master switch top target gene signaling network controlling cancer suppression
2017/10/25
There are two important categories of genes involved in cancer development, oncogenes and tumor suppressor genes. When oncogenes gain function, e.g. through mutation, they actively promote cancer – dr...
UA Cancer Center Team Identifies a Switch that May Help Target Dormant Cancer Cells（图）
UA Cancer Center Team Dormant Cancer Cells
2017/10/24
A study by scientists at the University of Arizona and the University of Pittsburgh may hold the key to targeting dormant — or inactive —cancer cells, which are resistant to chemotherapy and other tre...
Light-scattering tool peers into pancreas to find cancer
Light-scattering tool pancreas cancer
2017/7/24
Pancreatic cancer is difficult to detect early because the pancreas is deep inside the abdomen, making potentially cancerous cells hard to reach and identify without surgery.Researchers funded by the ...
A research study led by University of Minnesota engineers gives new insight into how cancer cells move based on their ability to sense their environment. The discovery could have a major impact on the...
Nuclear transfer of mitochondrial DNA in colon and rectal cancer
Nuclear transfer mitochondrial DNA colon and rectal cancer
2017/4/27
Patients with colon and rectal cancer have somatic insertions of mitochondrial DNA into the nuclear genomes of the cancer cells, University of Alabama at Birmingham researchers report in the journal G...
Biomedical engineers at Duke University have discovered a way to detect signs of cancer on a cell-by-cell basis using two lasers and a camera.Several medical devices currently in use and in clinical t...
Penn/Wistar Study Finds ‘Sweet Spot’ Where Tissue Stiffness Drives Cancer’s Spread
Penn/Wistar Study Sweet Spot Tissue Stiffness Cancer’s Spread
2017/3/14
In order for cancer to spread, malignant cells must break away from a tumor and through the tough netting of extracellular matrix, or ECM, that surrounds it. To fit through the holes in this net, thos...
Tumor-targeting system uses cancer’s own mechanisms to betray its location
Tumor-targeting system cancer’s own mechanisms betray its location
2017/3/13
By hijacking a cancer cell’s own metabolism, researchers have found a way to tag and target elusive cancers with small-molecule sugars. This opens treatment pathways for cancers that are not responsiv...
Testing treatments for bone cancer tumors may get easier with new enhancements to sophisticated support structures that mimic their biological environment, according to Rice University scientists.A te...
Testing treatments for bone cancer tumors may get easier with new enhancements to sophisticated support structures that mimic their biological environment, according to Rice University scientists.A te...
Common Breast Cancer Mutation Could Be Vulnerable to Drug Combination
Common Breast Cancer Vulnerable Drug Combination
2016/12/27
Breast cancer cells that carry a certain gene mutation can be induced to die using a combination of an existing targeted therapy along with an investigational molecule tested by Duke Cancer Institute ...
Cancer cells 'talk' to their environment,and it talks back
Cancer cells talk environment talks back
2016/11/29
Interactions between an animal cell and its environment, a fibrous network called the extracellular matrix, play a critical role in cell function, including growth and migration. But less understood i...
Carnegie Mellon Algorithm Characterizes How Cancer Genomes Get Scrambled
Carnegie Mellon Algorithm Characterizes Cancer Genomes
2016/8/1
A new method for analyzing the scrambled genomes of cancer cells allows researchers, for the first time, to simultaneously identify two different types of genetic changes associated with cancers and t...
Chronic inflammation in the gut increases the risk of colon cancer by as much as 500 percent, and now Duke University researchers think they know why.Their new study points to a biomarker in the cellu...