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A context dependent pair hidden Markov model for statistical alignment
Comparative genomics Contextual alignment DNA sequence alignment EM algorithm
2011/7/19
This article proposes a novel approach to statistical alignment of nucleotide sequences by introducing a context dependent structure on the substitution process in the underlying evolutionary model. W...
Sparsity considerations for dependent observations
Sparsity considerations dependent observations
2011/3/18
The aim of this paper is to provide a comprehensive introduction for the study of L1-penalized estimators in the context of dependent observations. We define a general $\ell_{1}$-penalized estimator f...