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Researchers have identified a single, simple metric to inform medication regimen design that could bring an entire arsenal of first-line antibiotics back into the fight against drug-resistant pathogen...
Background: Since 2001, anti-retroviral therapy (ART) has been provided to over 75,000 HIV-infected patients at the USAID-Academic Model Providing Access to Healthcare (AMPATH) Partnership in western ...
A simple, sensitive and precise green high-performance liquid chromatographic method including on-line pre-column oxidation combined by column switching with a short Hypersil ODS analytical column (10...
Introduction: Bile duct complications are common after liver transplantation. The impact of preservation solution is unclear. Aim: We investigated the impact of different preservation solutions with a...
Aims and Background: Irinotecan is a standard option for relapsed/refractory advanced colo- rectal cancer. Combination with raltitrexed and irinotecan at lower than MTD doses should preserve disease s...
The authors consider detection of high-energy photons in positron emission tomography using thick scintillation crystals.Parallax effect and multiple Compton interactions in such crystals significant...
The authors consider detection of high-energy photons in positron emission tomography using thick scintillation crystals.Parallax effect and multiple Compton interactions in such crystals significant...
The localized coherent line removal algorithm reduces CPR-artifacts in VF-ECG, but does not eliminate them. Our SNR-improvements are in the same range as offered by multichannel methods of Rheinberger...
Current computed tomography (CT) scanners, including micro-CT scanners, utilize a point x-ray source. As we target higher and higher spatial resolutions, the reduced x-ray focal spot size limits the t...
DNA fragmentation is a biochemical hallmark of apoptosis. Several endonucleases, including CAD/DFF40 and endonuclease G, are implicated in DNA fragmentation. DNase γ has also been considered to be one...
Objective: To study the effect of 3`-azido-3`-deoxythymidine (AZT) on telomerase activity and the proliferation of ovarian cancer cells in vitro. Methods: Telomerase activity was detected by enzyme ...
Cisplatin (CDDP) is an effective anticancer agent that is widely used in the treatment of testicular, ovarian, bladder and lung cancers. However the development of resistance to CDDP by tumor cells is...
The immune system is a target of dibutyltin (DBT) intoxication. We evaluated the effects of DBT dichloride in macrophages using the murine macrophage cell line, J774.1. Cultured J774.1 cells were expo...
Immunotoxicity is one of toxic effects of dibutyltin(DBT)compounds. In our previous study, the inhibitory effects of DBT on the productions of tumor necrosis a(TNFα)and interleukin-1β in a murine macr...

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