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Postprandial response of activated factor VII in elderly women depends on the R353Q polymorphism
Coagulation diet genetics
2016/6/1
Activated factor VII (FVIIa) is a very potent coagulant
and may be a key determinant of the outcome of a cardiovascular
event. The main determinants of FVIIa are the R353Q
polymorphism and dietary ...
Dietary oleic and palmitic acids and postprandial factor VII in middle-aged men heterozygous and homozygous for factor VII R353Q polymorphism
Factor VII palmitic acid postprandial lipemia
2016/5/30
The R353Q genotype is a major determinant of
factor VII coagulant (FVIIc) activity, which is associated with an
increased risk of ischemic heart disease (IHD) and elevated
plasma triacylglycerol co...
The relation of magnesium and calcium intakes and a genetic polymorphism in the magnesium transporter to colorectal neoplasia risk 1,2,3
Magnesium calcium ratio of magnesium to calcium intake
2009/4/20
Background: Mean magnesium intake in the US population does not differ from that in East Asian populations with traditionally low risks of colorectal cancer and other chronic diseases, but the ratio...
A functional 19-base pair deletion polymorphism of dihydrofolate reductase (DHFR) and risk of breast cancer in multivitamin users
Folate dihydrofolate reductase DHFR one-carbon metabolism breast cancer multivitamins prospective study
2008/12/12
Background:Dihydrofolate reductase (DHFR) converts dihydrofolate (DHF) into tetrahydrofolate (THF) and plays an essential role in cell metabolism and cellular growth. Folic acid from multivitamins nee...
-Linolenic acid, 6-desaturase gene polymorphism, and the risk of nonfatal myocardial infarction1,2,3
Myocardial infarction genetics diet fatty acids epidemiology
2008/12/12
Background:6-Desaturase (FADS2) is the rate-limiting step in the polyunsaturated fatty acid (PUFA) biosynthetic pathway.Objective:The aim was to test whether the common deletion [T/-] in the promoter ...
The D1822V APC polymorphism interacts with fat, calcium, and fiber intakes in modulating the risk of colorectal cancer in Portuguese persons1,2,3
Colorectal cancer diet genetic polymorphism lifestyle factors
2008/12/10
Background: Both genetic and environmental factors affect the risk of colorectal cancer (CRC). Objective: We aimed to examine the interaction between the D1822V polymorphism of the APC gene and dietar...
Polymorphism exon 1 variant at the locus of the scavenger receptor class B type I gene: influence on plasma LDL cholesterol in healthy subjects during the consumption of diets with different fat contents
dietary intervention LDL cholesterol genetic polymorphism
2016/12/30
The objective of the study was to determine whether the exon 1 variant (G→A) at the SRB-I gene is associated with the lipid response to the content and quality of dietary fat in healthy subjects.
Effect of transferrin polymorphism on the metabolism of vitamin C in Zimbabwean adults
Africa transferrin phenotype vitamin C L-ascorbic acid iron status scurvy blacks
2016/12/17
Background: Transferrin is the major iron binding protein in human plasma. In black persons, the transferrin CD phenotype has been associated with alterations in certain markers of iron status.Ob...
Polyunsaturated fatty acids modulate the effects of the APOA1 G-A polymorphism on HDL-cholesterol concentrations in a sex-specific manner:the Framingham Study
Polyunsaturated fatty acids modulate APOA1 G-A polymorphism HDL-cholesterol concentrations sex-specific manner Framingham Study
2016/12/17
Background: A common G-to-A substitution in the promoter area (−75 base pairs) of the apolipoprotein A-I gene (APOA1) has been described. The A allele was shown to be associated w...