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Human papillomavirus type distribution in cervical cancer in Indiana and Botswana
in the Department of Biochemistry and Molecular Biology,Indiana University
2015/5/25
In this study we compared the distribution of HPV types in cervical cancer specimens from women living in either Indiana or Botswana. Paraffin-embedded blocks of formalin-fixed cervical cancer specime...
HPV VACCINES AND THE AUSTRALIAN HUMAN PAPILLOMAVIRUS (HPV) VACCINATION PROGRAM
Human papillomavirus (HPV) vaccine HPV
2015/3/26
Australia was the first country in the world to commence a national vaccination program against human papillomavirus,
using the quadrivalent human papillomavirus vaccine, Gardasil®. This program...
Mapping the human body: the importance of cross-disciplinary thinking
Mapping the human body cross-disciplinary thinking
2015/3/23
The history of scientific thought is marked by spikes of revolutionary thinking, followed by periods of evolutionary consolidation. Both are essential components in the continued development of our un...
Efficacy of Recombinant Adenoviral Human p53 Gene in Treatment of Malignant Pleural or Peritoneal Effusions
p53 gene Gene therapy Malignant effusion Intra-cavity infusion
2013/12/4
Background and objective Once the malignant pleural or peritoneal effusion is developed it is difficult to control. This report presents a new method for controlling the malignant effusions.
Me...
Surprising similarities between human and zebrafish tumors（图）
Surprising similarities human tumors zebrafish tumors
2010/10/13
Most human cells have 23 pairs of chromosomes, the large bundles of DNA that store all of a cell’s genetic information. However, scientists realized more than 100 years ago that tumor cells usually ha...
Cytotoxic effects of caffeic acid phenethyl ester (CAPE) on the human multiple myeloma cell line
Caffeic acid phenethyl ester (CAPE) multiple myeloma cytotoxicity IL-6
2010/1/11
Aim: Caffeic acid phenethyl ester (CAPE) has cytotoxic, apoptotic, and antiproliferative effects on various tumor cells, and is the most active component of propolis. This study aimed to examine the i...
Genetic Fingerprint Concerned with Lymphatic Metastasis of Human Lung Squamous Cancer
Lung neoplasms Gene-expression Lymphatic metastasis
2013/12/10
Background and objective With the most recent introduction of microarray technology to biology, it becomes possible to perform comprehensive analysis of gene expression in cancer cell. In this study t...
Heparanase Expression Correlates with Angiogenesis and Lymphangiogenesis in Human Lung Cancer
Lung Neoplasms Heparanase Vascular Endothelial Growth Factor-C Lymphatic Metastasis
2013/12/10
Background and objective Heparanase has been thought to be a good molecular marker of tumor, and the heparanase expression level correlated closely with tumor metastasis. In this study, we investigate...
SYNERGISTIC ANTITUMOR EFFECT OF ASCORBIC ACID,LYSINE,PROLINE,AND EPIGALLOCATECHIN GALLATE ON HUMAN FIBROSARCOMA CELLS HT-1080
Antitumor activity ascorbic acid cell proliferation cytotoxicity EGCG fibrosarcoma lysine Matrigel invasion matrix metalloproteinases MMP MMP-2 MMP-9 MMP-inhibitors MTT assay nutrient synergy proline toxicity
2009/7/15
Introduction: Matrix metalloproteinases (MMPs) have received much attention in recent years for their role in various malignancies, and have been implicated in tumor invasion, metastasis and angiogene...
IN VIVO AND IN VITRO ANTITUMOR EFFECT OF NUTRIENT SYNERGY ON HUMAN OSTEOSARCOMA CELL LINE MNNG-HOS
Ascorbic acid epigallocatechin gallate lysine Matrigel invasion MMP MNNG-HOS nude mice nutrient synergy osteosarcoma prognosis proline treatment
2009/7/15
Current treatment of osteosarcoma is associated with poor prognosis, especially due to the increased risk of developing other cancers with chemotherapy. Therefore, new safe effective treatment strateg...
Analysis of K-Ras Oncogene Codon 12 Mutations in a Series of Human Lung Cancers
K-ras codon 12 mutations on small cell lung cancers
2009/6/30
Lung cancer is the major cancer in Turkey; 45% of the deaths due to cancer in Turkish males are from lung cancer. There are 8 histopathological types of lung cancer, and most types have several genomi...
Detection of Human Papilloma Virus in Benign,Malignant and Pre-Cancerous Lesions of Oral Mucosa By in Situ Hybridization
HPV In situ hybridization oral lesions
2009/6/29
HPV is an epitheliotropic virus, predominantly associated with human skin and mucosal lesions. In many studies, the presence of HPV types 6/11, 16/18 and 31/33/51 have been demonstrated in oral lesion...
Human Herpesvirus 8 (HHV-8) in Non-HIV Associated Forms of Kaposi's Sarcoma from Turkey
Kaposi's sarcoma Human herpesvirus-8
2009/6/29
Objective: Kaposi's sarcoma (KS), first described in 1872 by Moritz Kaposi, is a spindle cell, multifocal vascular tumor. Despite the intense work on the pathogenesis of KS, its etiology remains in d...
Detection of Human Papillomavirus Infection in Esophageal Carcinomas by the Histopathological Method and Polymerase Chain Reaction Technique
Esophagus cancer Human Papillomavirus
2009/6/26
A series of 30 surgical resection materials of patients with squamous cell carcinoma (SCC) and 10 with adenocarcinoma (AC) were analyzed histologically and by polymerase chain reaction (PCR) to demons...
Gene Therapy in Human Breast Cancer
gene therapy breast cancer viral vectors vector targeting
2009/6/26
Gene therapy, being a novel treatment for many diseases, is readily applicable for the treatment of cancer patients. Breast cancer is the most common cancer among women. There are many clinical protoc...