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Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2−/− mice
podosome organization bone density osteoclast functions
2014/11/6
The protein tyrosine kinase Pyk2 is highly expressed in osteoclasts, where it is primarily localized in podosomes. Deletion of Pyk2 in mice leads to mild osteopetrosis due to impairment in osteoclast ...
The influence of cigarette smoke inhalation on bone density:a radiographic study in rats
Smoking Bone density Rats Wistar
2009/10/19
The aim of this study was to evaluate the influence of cigarette smoke inhalation (CSI) and its cessation on tibiae bone quality. Forty-one male Wistar rats were randomly assigned to one of the follow...
Masticatory Demands Induce Region-Specific Changes in Mandibular Bone Density in Growing Rats
Mastication Food consistency Bite block Bone mineral density Mandible Mechanical loading
2008/12/1
This study investigates the structural adaptation of the mandibular bone when subjected to different masticatory functional and mechanical demands during growth. The effect of two experimental fac...