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Evaluation of Novel Scoring System Named 5-5-5 Exacerbation Grading Scale for Allergic Conjunctivitis Disease
allergic conjunctivitis atopic keratoconjunctivitis clinical severity score vernal keratoconjunctivitis
2010/11/16
The median severity scores of the 5-5-5 exacerbation grading scale in VKC, AKC and AC were 243 (range: 12-444), 32.5 (11-344), and 13 (2-33), respectively. The severity score of each ACD disease type ...
Clinical Evaluation of Total IgE in Tears of Patients with Allergic Conjunctivitis Disease Using a Novel Application of the Immunochromatography Method
allergic conjunctivitis disease immunochromatography immunoglobulin E
2010/11/16
The positive ratio obtained by this novel application of the immunochromatography assay was 38 of the 41 in the patients with ACD and none in the 7 controls. IgE indices for the VKC group, AKC group a...
Awarded Article, Annual Meeting of JSA Fibroblasts as Local Immune Modulators in Ocular Allergic Disease
conjunctiva cornea cytokine fibroblast vernal keratoconjunctivitis
2010/11/18
Vernal keratoconjunctivitis (VKC), a severe form of ocular allergic disease, is characterized by the formation of giant papillae at the upper tarsal conjunctiva and corneal lesions that threaten visio...
Increased incidence of allergic disorders and elevated food-specific serum IgG4 levels in Japanese patients with Crohn's disease
allergic disorder food allergy IgE IgG4 inflammatory bowel disease
2010/11/29
An allergic response to foreign intestinal antigens such as those contained in food has been implicated as a causative factor in the development of inflammatory bowel disease (IBD). In this study, we ...
Recent Developments in Genetic Study of Allergic Disease in the Japanese Population
allergic disease asthma atopy Japanese linkage polymorphism
2010/11/19
Allergy is a common immune disorder characterized by raised IgE levels, which leads to clinical disorders such as asthma, rhinitis and eczema. Our understanding of the pathogenesis of allergic disease...
IL-13/IL-13 Receptor Interaction, an Emerging Therapeutic Target in Allergic Disease
allergy antagonist asthma drug design interleukin-13 receptor
2010/11/19
Interleukin (IL)-13 is a Th-2 cytokine, known to be involved in allergic diseases. Although IL-13 and another Th-2 cytokine, IL-4, share receptors and signal pathways, having similar biological proper...
