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Background: Glucose is a natural ligand for sweet taste receptors (STRs) that are expressed on the tongue and in the gastrointestinal tract. Whether STRs directly contribute to the regulation of gluco...
The 2017 GRC and GRS on Inhibition in the CNS aim to increase our understanding of the fundamental mechanisms contributing to the critical role of inhibitory neurotransmission in normal and abnormal C...
Increased permeability of the blood-brain barrier (BBB) is important in neurological disorders. Neuroinflammation is associated with increased BBB breakdown and brain injury. Tumor necrosis factor-alp...
Neuroinflammation is one of the key pathological events involved in the progression of brain damage caused by cerebral ischemia. Metabolism of arachidonic acid through cyclooxygenase (COX) enzymes is ...
The DNA base excision-repair pathway is responsible for the repair of DNA damage caused by oxidation/alkylation and protects cells against the effects of endogenous and exogenous agents. Removal of th...
Drug-induced liver injury (DILI) limits the development and application of many therapeutic compounds and presents major challenges to the pharmaceutical industry and clinical medicine. Acetaminophen-...
In the present study the distribution of rubella hemagglutination inhibition (HI) antibody titer in the sera of 1486 women of 18 to 25 years old residing in Tehran were examined. Sera were pretreated ...
Angiotensin converting enzyme (ACE) inhibitors have been known to inhibit the effects of angiotensin II which increases the vascular resistance. In this study, we studied the acute effects of a single...
Many studies have established the therapeutic benefits of angiotensin-converting enzyme (ACE) inhibitors such as reducing reperfusion arrhythmias, and angiotensin II type 1 (AT1) blocker may have simi...
Corneal neovascularization (NV) is a significant, sight-threatening, complication of many ocular surface disorders. Presence of new vessels in cornea can compromise clarity and thus vision. The data s...
期刊信息 篇名 Amiloride inhibition of glycinergic mIPSCs in mechanically dissociated rat spinal neurons 语种 英文 撰写或编译 作者 Li Y,Li YF,Xu TL 第一作者单位 刊物名称 Neuroscience Letter 页面 2003, 349:17-20 出版日期 2003年 月 日 文章标识...
期刊信息 篇名 Inhibition of glycine response by amiloride in rat spinal neurons 语种 英文 撰写或编译 作者 Li YF,Li Y,Xu TL 第一作者单位 刊物名称 Neuroscience Letter 页面 2003, 345:173-176 出版日期 2003年 月 日 文章标识(ISSN) 相关项目 GABAa受体与甘氨...
期刊信息 篇名 Asymmetric cross-inhibition between GABAA and glycine receptors in rat spinal dorsal horn neurons 语种 英文 撰写或编译 作者 Li Y,Wu LJ,Legendre P,Xu TL 第一作者单位 刊物名称 Journal of Biological Chemistry 页面 2003...
Background: Epinastine hydrochloride and fexofenadine hydrochloride, the second-generation antihistamines, are largely used in the indication of allergic rhinitis in Japan. The purpose of this study w...
Agents that increase intracellular cyclic 3',5'-adenosine monophosphate (cAMP), such as forskolin, prostaglandin (PG)E2, salbutamol and 8-bromo-cAMP, have been shownto inhibit the proliferation of air...

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