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The Effect of H1 Antagonists Carebastine and Olopatadine on Histamine Induced Expression of CC Chemokines in Cultured Human Nasal Epithelial Cells
allergic rhinitis carebastine CC chemokine histamine human nasal epithelial cells monocyte chemotactic protein-1 olopatadine RANTES
2010/11/18
The release of RANTES and MCP-1 was significantly upregulated by histamine compared with the control group. Both carebastine and olopatadine inhibited the release of CC chemokine production to the con...
Effect of histamine H1 receptor antagonists on antigen-induced increase of cough sensitivity in guinea pigs
allergic reaction capsaicin cough sensitivity guinea pig histamine H1 receptor antagonists
2010/11/26
Eosinophilic airway inflammation and increased cough sensitivity without bronchial hyperresponsiveness are the pathologic and physiologic features of bronchodilator-resistant non-productive cough-asso...
Permeability of rat IgE across rat aortic endothelial cell is enhanced by histamine
IgE endothelial cells histamine permeability
2010/11/25
On the basis of results from the present study, histamine, acting via H2 receptors, enhances the permeability of rat IgE across the RAEC mono-layer. The increased permeability of endothelial cells ind...
Effect of Epinastine Hydrochloride, a Second-generation Histamine H1-receptor Antagonist, on Sensory Neurons in vitro
epinastine histamine H1 antagonists nerve growth factor substance P
2010/11/22
Background: Epinastine hydrochloride (epinastine) is a second-generation histamine H1-receptor antagonist widely used as an anti-allergic and anti-pruritic. To explore possible new aspects of the anti...