搜索结果: 1-9 共查到“医学细胞生物学 Mechanical”相关记录9条 . 查询时间(0.059 秒)
Effects of 1 to 3 years' treatment with alendronate on mechanical properties of the femoral shaft in a canine model: implications for subtrochanteric femoral fracture risk
subtrochanteric fractures femur bisphosphonates
2014/12/4
Bisphosphonate (BP) treatment used to prevent bone loss in postmenopausal osteoporosis has recently been implicated in an apparent increase in subtrochanteric femoral fractures. Previous work showed t...
Changes in non-enzymatic glycation and its association with altered mechanical properties following 1-year treatment with risedronate or alendronate
bisphosphonates alendronate animal models
2014/12/4
Summary One year of high-dose bisphosphonate (BPs) therapy in dogs allowed the increased accumulation of advanced glycation end-products (AGEs) and reduced postyield work-to-fracture of the cortical b...
Nanoscale Changes in Collagen are Reflected in Physical and Mechanical Properties of Bone at the Microscale in Diabetic Rats
Zucker diabetic Sprague–Dawley Atomic Force Microscopy Raman Spectroscopy
2014/12/4
Diabetes detrimentally affects the musculoskeletal system by stiffening the collagen matrix due to increased advanced glycation end products (AGEs). In this study, tibiae and tendon from Zucker diabet...
Heritability of Lumbar Trabecular Bone Mechanical Properties in Baboons
mechanical properties nonhuman primate skeletal genetics
2014/12/4
Genetic effects on mechanical properties have been demonstrated in rodents, but not confirmed in primates. Our aim was to quantify the proportion of variation in vertebral trabecular bone mechanical p...
Reference-Point Indentation Correlates with Bone Toughness Assessed Using Whole-Bone Traditional Mechanical Testing
bone mechanical testing material properties
2014/12/4
Traditional bone mechanical testing techniques require excised bone and destructive sample preparation. Recently, a cyclic-microindentation technique, reference-point indentation (RPI), was described ...
In vivo reference point indentation reveals positive effects of raloxifene on mechanical properties following six months of treatment in skeletally mature beagle dogs
bone remodeling bone mechanics osteoporosis treatments indentation
2014/12/4
Raloxifene treatment has been shown previously to positively affect bone mechanical properties following one year of treatment in skeletally mature dogs. Reference point indentation (RPI) can be used ...
Can Deterministic Mechanical Size Effects Contribute to Fracture and Microdamage Accumulation in Trabecular Bone?
microdamage biomechanics fracture
2014/12/4
Failure of bone under monotonic and cyclic loading is related to the bone mineral density, the quality of the bone matrix, and the evolution of microcracks. The theory of linear elastic fracture mecha...
Cortical Bone Mechanical Properties Are Altered in an Animal Model of Progressive Chronic Kidney Disease
chronic kidney disease whole bone mechanical properties
2014/12/4
Chronic kidney disease (CKD), which leads tocortical bone loss and increasedporosity,increases therisk of fracture. Animal models have confirmed that these changes compromise whole bone mechanical pro...
Mechanical strain-induced DNA synthesis and cell proliferation in human airway smooth muscle cells through extracellular signal-regulated kinase
airway smooth muscle cell extracellular signal-regulated kinase mechanical strain
2010/11/25
An increased airway muscle content is one of the characteristic features of airway remodeling. Proinflammatory substances, growth factors and mechanical strain promote airway muscle cell proliferation...
