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Evaluation of p53 and Bcl-2 genes and proteins expression in human breast cancer T47D cells treated with extracts of Astrodaucus persicus (Boiss.) Drude in comparison to Tamoxifen
Astrodaucus persicus T47D cells p53 and Bcl-2 gens RT-PCR Immunocytochemistry
2009/11/26
Background and purpose of the study:Screening of different plant components for new anticancer drugs is one of the main research activities throughout the world. In this study, the anticancer effects ...
Technical Approach to Generate Polyclonal Antibodies Against Bacterially Expressed GST-PYK- C: Evaluation of Cross-Reaction and Recognition in Some Mammalian and Yeast Cell Lysates
pyk-2 Central Nervous System Molecular Cloning Gene Fusion Bacterial Proteins Antibody Formation Antibody Specificity Immunochemistry Immunoblot-ting
2009/7/1
Pyk-2 is a protein tyrosine kinase, highly expressed in human hippocampus, dentate gyrus and olfactory bulb. In this study, polyclonal antibodies against the C-terminal of pyk-2, starting from Pro-759...
Evaluation of Ocular Surface Changes Using Impression Cytology in Acne Vulgaris Patients
Acne vulgaris impression cytology tear fucntion tests
2009/6/30
Purpose: Acne vulgaris is a disease with no known ocular involvement and is most commonly seen in the younger population. The aim of this study was to examine the ocular surfaces of acne vulgaris pati...
Evaluation of Adjuvant Activities Using Human Antigen Presenting Cells in Vitro
adjuvant cAMP dendritic cells Notch ligand THP-1
2010/11/17
Background: Immunomodulators such as lipopolysaccharides (LPS) and forskolin change the nature of dendritic cells (DCs) to induce Th1 and Th2 cells, respectively, thereby designated Th1 or Th2 adjuvan...
Improved Case of Bronchial Asthma by Re-administration of Pranlukast from Montelukast: Evaluation of Eosinophilic Inflammation in the Peripheral Airway
asthma eosinophil cationic protein (ECP) eotaxin induced sputum Pranlukast
2010/11/22
Following the re-administration of Pranlukast, the clinical symptoms disappeared within a few days and pulmonary function improved within 4 weeks. Eosinophils in the induced sputum almost completely d...