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Synthesis and Calcium channel antagonist activity of Nifedipine analogues with Chloroindolyl substituent
Synthesis Calcium channel antagonist activity Nifedipine analogues Chloroindolyl substituent
2010/1/6
Various diester analogues of nifedipine in which the ortho nitrophenyl group at position 4 were replaced by 3-chloro-1H-2-indolyl substituent, were synthesized and evaluated as calcium antagonists on ...
Synthesis and smooth muscle Calcium channel antagonist effect of Alkyl, Aminoalkyl 1,4-Dihydro-2,6-Dimethyl-4-Nitroimidazole-3,5 Pyridine Dicarboxylates
Ca+² channel antagonist DHP Arylpiperazine
2009/12/29
The discovery that 1,4-dihydropyridine (DHP) class of calcium channel antagonist inhibits the Ca+² influx represented a major therapeutic advance in the treatment of cardiovascular diseases such ...
Effect of the Combination of Glibenclamide,an ATP-dependent Potassium Channel Blocker, and Metoprolol, a Cardioselective b-adrenoceptor Blocker,During Myocardial Infarction in Conscious Rats
Glibenclamide Metoprolol Arrhythmias Sudden cardiac death Conscious rats
2009/6/29
We investigated the possible interaction of glibenclamide and metoprolol on the occurrence of life threatening arrhythmias during the acute phase of experimental myocardial infarction. Coronary artery...
