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《中国药理学报》出版离子通道（Ion Channel）专刊
中国药理学报 离子通道专刊
2016/1/18
离子通道是一类跨膜的大分子孔道，可允许离子在电化学梯度驱动下穿过细胞膜，从而完成信号传导、细胞兴奋性调节等生理功能，现已成为当前药物研发中仅次于G蛋白偶联受体、蛋白激酶的第三大类药物靶点。
汕头大学医学院药理学课件 Calcium Channel Blockers (CCB)。
Synthesis and Calcium channel antagonist activity of Nifedipine analogues with Chloroindolyl substituent
Synthesis Calcium channel antagonist activity Nifedipine analogues Chloroindolyl substituent
2010/1/6
Various diester analogues of nifedipine in which the ortho nitrophenyl group at position 4 were replaced by 3-chloro-1H-2-indolyl substituent, were synthesized and evaluated as calcium antagonists on ...
Synthesis and smooth muscle Calcium channel antagonist effect of Alkyl, Aminoalkyl 1,4-Dihydro-2,6-Dimethyl-4-Nitroimidazole-3,5 Pyridine Dicarboxylates
Ca+² channel antagonist DHP Arylpiperazine
2009/12/29
The discovery that 1,4-dihydropyridine (DHP) class of calcium channel antagonist inhibits the Ca+² influx represented a major therapeutic advance in the treatment of cardiovascular diseases such ...
Effect of the Combination of Glibenclamide,an ATP-dependent Potassium Channel Blocker, and Metoprolol, a Cardioselective b-adrenoceptor Blocker,During Myocardial Infarction in Conscious Rats
Glibenclamide Metoprolol Arrhythmias Sudden cardiac death Conscious rats
2009/6/29
We investigated the possible interaction of glibenclamide and metoprolol on the occurrence of life threatening arrhythmias during the acute phase of experimental myocardial infarction. Coronary artery...
CONTROL OF ENVIRONMENTAL HEALTH AND REMOVAL OF RATS BY 2-ADRENERGIC ANTAGONIST AND POTASSIUM CHANNEL BLOCKER
KATP channel POTASSIUM CHANNEL BLOCKER
2010/4/6
In the present study, it is shown that in vivo oral administration of glibenclamide (1-10 mg/kg/day), an adenosine triphosphate -sensitive potassium channel blocker, and yohimbine (1-5 mg/kg/day), an ...
