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Gene Expression Profiles of BAD and Bcl-xL in the CA1 Region of the Hippocampus Following Global Ischemic/Reperfusion and FK-506 Administration
Ischemic/Reperfusion Real-Time RT-PCR Hippocampus Tacrolimus Bcl-xL Gene BAD
2015/12/29
Background: The hippocampus is a tiny nub in the mammalian brain that is involved in forming, organizing, and storing memories. Global cerebral ischemia (GCI) and reperfusion induced apoptosis lead to...
Evaluating Glucocorticoid Administration on Biomechanical Properties of Rats’ Tibial Diaphysis
Glucocorticoids Biomechanical Phenomena Rats Tibia
2015/10/22
Background: Osteoporosis is a disease, which causes bone loss and fractures. Although glucocorticoids effectively suppress inflammation, their chronic use is accompanied by bone loss with a tendency t...
Intravenous Self-Administration of Alcohol in Selectively Bred High- and Low- Alcohol Preferring Mice
Genetic vulnerability alcoholism gene alcohol dependence animal model genetic vulnerability
2015/1/9
Genetic vulnerability to alcoholism is theorized to be caused by multiple interacting genetic loci, each with a small to modest effect combining under certain environmental influences to contribute to...
ALTERATIONS IN THE SEEKING AND SELF-ADMINISTRATION OF ETHANOL AND ANXIETY-LIKE BEHAVIOR FOLLOWING EXPOSURE TO YOHIMBINE IN RATS SELECTIVELY BRED FOR HIGH ALCOHOL INTAKE
Alcohol Anxiety Relapse Selective Breeding Stress Yohimbine
2015/1/9
Stress has been shown to contribute to alcohol drinking; however, inconsistencies in both the clinical and pre-clinical literature speak to the need for better paradigms to study this interaction. The...
Barberry Administration and Pro-Oxidant–Antioxidant Balance in Patients With Metabolic Syndrome
Metabolic Cardiovascular Syndrome Berberidaceae Randomized Controlled Trial
2015/10/16
Background: Metabolic syndrome is the constellation of several cardiometabolic risk factors, and is associated with a heightened risk of coronary heart disease (CHD). The pro-oxidant–antioxidant balan...
Effects of Losartan and Vanillic Acid Co-Administration on Ischemia-Reperfusion-Induced Oxidative Stress in Isolated Rat Heart
Oxidative Stress Injury Vanillic Acid Losartan
2015/10/13
Background: Experimental studies have demonstrated that angiotensin II (ANG-II)-induced oxidative stress contributes to the pathogenesis of I/R injury.
Analgesic Effect of Low Dose Subcutaneous Ketamine Administration Before and After Cesarean Section
Ketamine Caesarean Section Pain Postoperative Diclofenac
2015/10/12
Background:: Pain is considered as an importantissue after cesarean section. Multimodal approach to post cesarean pain management may not only enhance analgesia but also reduce side effects after the ...
Co-administration of Grape Seed Extract and Exercise Training Improves Endothelial Dysfunction of Coronary Vascular Bed of STZ-Induced Diabetic Rats
Diabetic Vascular Complication Grape Seed Extract Exercise Coronary Vessels
2015/10/9
Background: One of the known complications of diabetes mellitus is vascular dysfunction. Inability of the coronary vascular response to cardiac hyperactivity might cause a higher incidence of ischemic...
Effect of Pentoxifylline Administration on Mast Cell Numbers and Degranulation in a Diabetic and Normoglycemic rat Model Wound Healing
Pentoxifylline Mast cells Diabetes Mellitus Wound Healing
2015/9/28
Background: Wound healing is a complicated and integrated process. Researches in the molecular level on human and animal models have indicated several molecular changes related to the effect of diabet...
Prevention of Methylprednisolone Acetate-Induced Osteoporosis with Calcium Administration in Rat Model
Methylprednisolone acetate osteoporosis bone metabolism markers (BMM) and rat
2009/11/24
Glucocorticoid steroids are widely used as anti-inflammatory and immunosuppressive medications and are well known to induce osteoporosis. In Present study 24 rats were randomly divided into four group...
Administration of Granulocyte Colony Stimulating Factor (G-CSF) in Experimentally Infected Rats
G-CSF E.coli sepsis neutropenia
2009/7/2
We investigated the effect of antibiotic or G-CSF plus antibiotic therapy given to E. coli septic rats. In our study, 80 rats were inoculated transperitoneally with 1 ml of a solution containing 10 7 ...
Effects of Acute Grayanotoxin-I Administration on Hepatic and Renal Functions in Rats
Grayanotokxin glutamic pyruvic transaminase (GPT) g-glutamyl transferase (g -GT) lactate deyhdrgenase (LDH)3 serum total protein
2009/6/30
The effects of acute Grayanotoxin-I (GTX-I) administration on hepatic and renal functions in rats were investigated. GTX-I was administrated to the animals of groups 1, 2 and 3 at a single i.p. dose o...
Improved Case of Bronchial Asthma by Re-administration of Pranlukast from Montelukast: Evaluation of Eosinophilic Inflammation in the Peripheral Airway
asthma eosinophil cationic protein (ECP) eotaxin induced sputum Pranlukast
2010/11/22
Following the re-administration of Pranlukast, the clinical symptoms disappeared within a few days and pulmonary function improved within 4 weeks. Eosinophils in the induced sputum almost completely d...