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Knowledge of the molecular and cellular mechanisms of ischemic injury is necessary for understanding acute kidney injury and devising optimal treatment regimens. The cortical actin cytoskeleton in the...
Background: Renal ischemia/reperfusion injury (IRI) is a major problem in renal transplantation, which occurs during the process of organ retrieval and storage, and is closely associated with acute re...
Background: Experimental studies have demonstrated that angiotensin II (ANG-II)-induced oxidative stress contributes to the pathogenesis of I/R injury.
Background: Myocardial infarction is one of the important causes of death during old ages. Gallic acid as an antioxidant or cyclosporine A (CsA) as inhibitor of mitochondrial permeability transition p...
Vascularization of the pancreatic allograft depends on the mesenteric and celiac arteries. During procurement inadvertent sectioning of the branches to the head of the pancreas can lead to ischemia an...
Background and purpose of the study: Probable antiarrhythmic effects of Cynodon dactylon (L.) pers. (family Poaceae) against ischemia/reperfusion (I/R)-induced arrhythmias were investigated in isolate...
Renal ischemia-reperfusion (IR) injury is a common problem in kidney transplantation. There is increasing evidence about the role of the reactive oxygen species (ROS) in these injuries and endogenous ...
Background: Dimethyl sulfoxide (DMSO) has been used as a solvent for many drugs in ischemic experiments. DMSO has many biological benefits, including antioxidant, anti-inflammatory, platelet aggregati...
Background: Dimethyl sulfoxide (DMSO) has been used as a solvent for many drugs in ischemic experiments. DMSO has many biological benefits, including antioxidant, anti-inflammatory, platelet aggregati...
In the striatum, large aspiny (LA) interneurons survive transient cerebral ischemia while medium spiny (MS) neurons die. Excitotoxicity is believed to be the major cause for neuronal death after ische...
Timely imaging and accurate interpretation of cerebral ischemia are required to identify patients who might benefit from more aggressive therapy, and nuclear medicine offers a noninvasive method for d...
This review considers the pathophysiology of air embolism that occurs as a result of diving and iatrogenic accidents. Various experimental therapies are classified according to their potential mechani...
Effects of hyperbaric oxygen (HBO) on acute cerebral ischemia were studied in spontaneously hypertensive rats, which had the carotid artery bilaterally ligated. The animals were exposed to HBO (100per...
The border between the gray and white matter is defined by an abrupt change in average blood flow. This difference allows one to distinguish structure with [14C]iodoantipyrine autoradiography. The ang...
Surgeons are confronted with ischemia-reperfusion (IR) injury more often than they anticipate. Hypoperfusion associated with hypotension and hypovolemia is probably the most common cause of non-occlus...

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