搜索结果: 1-15 共查到“医学 Genes”相关记录76条 . 查询时间(0.515 秒)
New genes linked to longer reproductive lifespan in women
CHEK1 CHEK2 new genes menopause DNA repair
2021/8/6
Scientists have identified nearly 300 gene variations that influence reproductive lifespan in women. Additionally, in mice, they have successfully manipulated several key genes associated with these v...
清华大学医学院郑撼球课题组在《基因与发育》（Genes ＆ Development）发表合作论文揭示抑制乳腺癌转移的关键因子（图）
清华大学医学院 郑撼球 基因与发育 Genes ＆ Development 论文 揭示抑制乳腺癌 转移 关键因子
2020/10/22
SNAI2蛋白是SNAIL转录因子家族重要的成员之一。最初在胚胎发育的研究中，发现其对关键发育阶段中细胞的形态改变和细胞迁移发挥重要的作用。随后的研究中发现上皮来源的肿瘤细胞只有在上调以SNAI2为代表的转录因子之后，将自己改变为类似成纤维细胞的“窄长”状，并去除细胞之间的粘连，才能获得强大的组织浸润和迁移能力，从而帮助肿瘤细胞实现离开原位组织并最终发生癌症转移。而在病人预后最差的三阴性乳腺癌中，...
为贯彻落实中央深改委《关于深化改革 培育世界一流科技期刊的意见》精神，由中国科协、财政部、教育部、科学技术部、国家新闻出版署、中国科学院、中国工程院等七部委联合启动了“中国科技期刊卓越行动计划”。“中国科技期刊卓越行动计划”以习近平新时代中国特色社会主义思想为指导，以建设世界一流科技期刊为核心目标，是迄今为止我国在科技期刊领域实施的力度最大、资金最多、范围最广的重大支持专项。
Obesity, genes, and sleep habits
Obesity genes sleep habits
2018/11/13
Obesity is a multifactorial health problem that remains an object of major preoccupation, partly because of the difficulty in deriving effective prevention and treatment strategies from recent researc...
New tool for combating mosquito-borne disease:insect parasite genes
combating mosquito-borne disease insect parasite genes
2017/3/14
Wolbachia is the most successful parasite the world has ever known. You’ve never heard of it because it only infects bugs: millions upon millions of species of insects, spiders, centipedes and other a...
Hippo通路与抗肿瘤免疫——浙江大学生命科学研究院赵斌实验室在Genes & Development发表文章阐释肝癌发生的重要机制（图）
Hippo通路 抗肿瘤免疫 浙江大学 赵斌实验室 Genes & Development 肝癌 肿瘤免疫
2017/3/6
近年来对肿瘤免疫的研究以及免疫疗法的发展为治愈癌症带来了一线曙光。研究发现机体的免疫系统特别是T细胞具有识别和对抗癌细胞的功能，然而在多种机制的作用下这一功能面对肿瘤常常缴械投降，最终肿瘤成功的发生发展。因此，全面阐明肿瘤细胞逃逸抗肿瘤免疫的机制是开发新方法重新调动机体免疫系统杀灭或预防肿瘤的关键。对于肿瘤免疫的研究大都针对已经形成的肿瘤，而因为技术上的难度，对肿瘤起始阶段的抗肿瘤免疫研究相对较少...
The Association Analysis between ACE and ACTN3 Genes Polymorphisms and Endurance Capacity in Young Cross-Country Skiers:Longitudinal Study
Genes polymorphisms endurance capacity skiing longitudinal study
2016/7/7
Endurance performance depends on the integration of several phenotypic traits influenced by multiple environmental and genetic factors. Objectives of the study were: (1) to examine the genotypic frequ...
Effects of isoenergetic high-carbohydrate compared with high-fat diets on human cholesterol synthesis and expression of key regulatory genes of cholesterol metabolism
glucose tolerance high-carbohydrate diet stable isotopes
2016/6/13
High-carbohydrate diets improve plasma cholesterol
concentrations but increase triacylglycerol concentrations;
the latter effect increases the risk of cardiovascular disease
(CVD). Triacylglycerol ...
Fox et al (1), after having compared Mexican Pima Indians
with non-Pima Mexicans living in the same traditional environment,
concluded that their own results do not support the hypothesis
that hypo...
Calcium and 1,25-dihydroxyvitamin D3 modulate genes of immune and inflammatory pathways in the human colon: a human crossover trial
1,25-dihydroxyvitamin D3 calcium colon gene expression Western diet
2018/11/29
Background: A high dietary calcium intake with adequate vitamin D status has been linked to lower colorectal cancer risk, but the mechanisms of these effects are poorly understood.
Novel regulation of neuronal genes implicated in Alzheimer disease by microRNA
Alzheimer APP BACE1 microRNA post-transcriptional gene regulation amyloid fetal neurons
2015/5/21
Alzheimer disease (AD) results, in part, from the excess accumulation of the amyloid-β peptide (Aβ) as neuritic plaques in the brain. The short Aβ peptide is derived from a large transmembrane precurs...
Light-activated genes might be precisely controlled and targeted（图）
Light-activated genes precisely controlled targeted
2015/3/4
Duke University researchers have devised a method to activate genes in any specific location or pattern in a lab dish with the flip of a light switch by crossing a bacterium’s viral defense system wit...
Protection of Human Lung Cells against Hyperoxia Using the DNA Base Excision Repair Genes hOgg1 and Fpg
oxygen toxicity DNA damage DNA repair
2014/12/12
Hyperoxia causes pulmonary toxicity in part by injuring alveolar epithelial cells. Previous studies have shown that toxic oxygen-derived species damage DNA and this damage is recognized and repaired b...
Inflammatory Genes and Psychological Factors Predict Induced Shoulder Pain Phenotype
CHRONIC,PAIN MUSCLE,PAIN INFLAMMATION,SNP IL1B TNF/LTA,REGION IL6
2017/5/24
The pain experience has multiple influences, but little is known about how specific biological and psychological factors interact to influence pain responses. The current study investigated the combin...
Genetic Analysis of cagA and vacA Genes in Helicobacter Pylori Isolates and Their Relationship with Gastroduodenal Diseases in the West of Iran
Helicobacter Pylori VacA Protein Helicobacter Pylori CagA protein Helicobacter Pylori
2015/10/12
Background: Helicobacter pylori have different virulence factors which are associated with several gastroduodenal diseases; however, this association is variable in different geographical regions. Dat...