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Construction of Recombinant Bacmid Containing M2e-Ctxb and Producing the Fusion Protein in Insect Cell Lines
Influenza Vaccines Baculovirus Cholera Toxin Subunit B
2015/10/10
Background:: Sequence variations in glycoproteins of influenza virus surface impel us to design new candidate vaccines yearly. Ectodomain of influenza M2 protein is a surface and highly conserved prot...
In Vitro Characterization of Docetaxel as a Radiosensitizer in Canine and Feline Cancer Cell Lines
Docetaxel Chemotherapy Radiation Therapy In Vitro
2013/2/19
An In Vitro study was conducted to investigate docetaxel as a radiation sensitizer in four canine (mammary carcinoma—CMT12 and CMT25, osteosarcoma—OS2.4, and transitional cell carcinoma—PTCC), and one...
Effects of aqueous garlic extract on oxidant/antioxidant status in 32D and 32Dp210 cell lines
Garlic mouse myeloid cell line oxidant/antioxidant status
2010/12/21
To investigate the possible effects of aqueous garlic extract on the oxidant/antioxidant status and apoptosis in 32D (wild type mouse myeloid cell = normal) and 32Dp210 (BCR-ABL fusion gene (+) mouse ...
Effects of aqueous garlic extract on oxidant/antioxidant status in 32D and 32Dp210 cell lines
Garlic mouse myeloid cell line oxidant/antioxidant status
2010/11/22
To investigate the possible effects of aqueous garlic extract on the oxidant/antioxidant status and apoptosis in 32D (wild type mouse myeloid cell = normal) and 32Dp210 (BCR-ABL fusion gene (+) mouse ...
Screening of prognostic factors using multiplex RT-PCR technique on different leukemic cell lines
Multiplex RT-PCR T-ALL oncogene leukemia cell
2009/12/18
Background: Leukemia is one of the most common pediatric malignancies. T-cell Acute Lymphoblastic Leukemia (T-ALL) accounts for 15% of hematopoetic cancers. It has been well understood that identifica...
Antitumor Effects of TNF-b,5-FU and Their Combinations on Cervical Carcinoma Cell Lines
TNF-b 5-FU ME180 HeLa Cervical Carcinoma
2009/6/26
Cervical carcinoma is one type of cancer with a high mortality rate in females. In this study, we investigated the cytotoxic effects of TNF-b, 5-FU and their combinations on human cervical carcinoma c...
Are Lymphoblastoid Cell Lines Suitable to Study Increased SMN Gene Expression by Histone Deacetylase Inhibitors?
Spinal muscular atrophy survival motor neuron gene histone deacetylase inhibitors treatment
2009/6/16
Aim: In this preliminary study, we aimed to analyze the effect of sodium butyrate (NB) and phenylbutyrate (PB), belonging to the class of histone deacetylase (HDAC) inhibitors, on lymphoblastoid cell ...
Construction of HeLa cell lines overexpressing metallothioneins-1 and -2 and their cytoprotective effects against oxidative damage induced by hydrogen peroxide
cell viability copper cytoprotective effect HeLa cell metallothionein
2009/4/1
It has been suggested that metallothioneins (MTs) play a role to protect cells from toxic effects of oxidative stress and heavy metals. On the other hand, the ability of Cu-containing MT to protect ce...
Antitumor effects of a combination of interferon-alpha and sorafenib on human renal carcinoma cell lines
interferon-alpha sorafenib human renal carcinoma cell lines
2009/3/2
To support the role of interferon (IFN)-α and sorafenib combination therapy against renal cell carcinoma (RCC), the effects of IFN-α and sorafenib on tumor growth, vascular endothelial growth factor...
Effects of gossypol on rat Sertoli and Leydig cells in primary culture and established cell lines
rat Sertoli Leydig cells established cell lines
2009/2/19
In order to evaluate the direct effect of gossypol on testicular cells, we used primary cultures of rat Leydig and Sertoli cells. No alteration in Leydig cell survival, morphology, or testosterone...
Anti-proliferative effect of the kinase inhibitor K252a on human prostatic carcinoma cell lines
Anti-proliferative effect kinase inhibitor K252a human prostatic carcinoma cell lines
2009/2/16
Members of the K252 family of kinase inhibitors have been demonstrated to inhibit a number of neurotrophin-mediated cellular responses, and to preferentially inhibit the activity of neurotrophin recep...
Immortalized testis cell lines from estrogen receptor（ER）alpha knock-out and wild-type mice expressing functional ERalpha or ERbeta
Immortalization HPV E6/E7 in vitro models
2008/12/29
The surprising findings that male mice lacking the estrogen receptor (ER) alpha (alphaERKO) have atrophic testis and are infertile proved that ERalpha is involved in normal testicular function. To o...
Effects of triptorelin, a gonadotropin-releasing hormone agonist, on the human prostatic cell lines PC3 and LNCaP
triptorelin a gonadotropin-releasing hormone agonist human prostatic cell lines PC3 LNCaP
2008/12/25
Some analogues of gonadotropin-releasing hormone (GnRH) influence the in vitro proliferation of cultured human cells by complex interactions that are only partially understood. This study explored t...
Effects of luteinizing hormone, follicle-stimulating hormone, and epidermal growth factor on expression and kinase activity of cyclin-dependent kinase 5 in Leydig TM3 and Sertoli TM4 cell lines
luteinizing hormone follicle-stimulating hormone growth factor kinase activity cyclin-dependent kinase 5
2008/12/25
We examined the effects of luteinizing hormone (LH), follicle-stimulating hormone (FSH), and epidermal growth factor (EGF) on the expression and kinase activity of cyclin-dependent kinase 5 (Cdk5)...
Initial predominance of the oxidative activity of type I 11beta-hydroxysteroid dehydrogenase in primary rat Leydig cells and transfected cell lines
Initial predominance oxidative activity 11beta-hydroxysteroid dehydrogenase Leydig cells transfected cell
2008/12/25
Glucocorticoids suppress testosterone production in Leydig cells. The level of glucocorticoid action is set within the Leydig cell by the number of glucocorticoid receptors and by the activity of ...
