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HOUSTON — (Oct. 31, 2014) — In the first study of its kind, Rice University researchers have mapped how information flows through the genetic circuits that cause cancer cells to become metastatic. The...
SIRT1 DEFICIENCY COMPROMISES MOUSE EMBRYONIC STEM CELL DIFFERENTIATION, AND EMBRYONIC AND ADULT HEMATOPOIESIS IN THE MOUSE
Mouse Embryonic Stem Cell Hematopoietic Cell Differentiation
2015/5/21
SIRT1 (Sirtuin 1) is a founding member of a family of seven proteins and histone deacetylases. It is involved in cellular resistance to stress, metabolism, differentiation, aging, and tumor suppressio...
Effects of Altering Cell Proliferation on Hematopoietic Stem and Progenitor Cell Function
hematopoietic progenitor cell cell cycle
2015/5/21
Cell cycle checkpoints guarantee movement through the cell cycle in an appropriate manner. The spindle assembly checkpoint (SAC) ensures the proper segregation of chromosomes into daughter cells durin...
Eicosanoid Regulation of Hematopoietic Stem and Progenitor Cell Function
AMD3100 G-CSF NSAID EP receptor Meloxicam
2015/5/21
dult hematopoietic stem cells (HSC) are routinely used to reconstitute hematopoiesis after myeloablation; however, transplantation efficacy and multilineage reconstitution can be limited by inadequate...