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Electrostatic Fields Near the Active Site of Human Aldose Reductase:1.New Inhibitors and Vibrational Stark Effect Measurements
apoptosis ATM cisplatin IKK p73 ubiquitination
2016/5/25
Vibrational Stark effect spectroscopy was used to measure electrostatic fields in the hydrophobic region of the active site of human aldose reductase (hALR2). A new hALR2 inhibitor was designed and sy...
Stark Spectroscopy of Donor-Acceptor Polyenes:Correlation with Nonlinear Optical Measurements
antitumor agents epothilones macrolactonization natural products total synthesis
2016/5/23
Stark Spectroscopy of Donor-Acceptor Polyenes:Correlation with Nonlinear Optical Measurements.
Ultrafast Measurements of Geminate Recombination of NO with Site-specific Mutants of Human Myoglobin
human myoglobin mutagenesis kinetics structure-function relationships picosecond timescale
2016/5/23
Flash photolysis studies of NO recombination to heme proteins offer a direct probe of protein structural changes on the tens of picoseconds timescale where they can be compared with molecular dynamics...
Characterization of the Overall and Internal Dynamics of Short Oligonucleotides by Depolarized Dynamic Light Scattering and NMR Relaxation Measurements
Overall and Internal Dynamics Short Oligonucleotides Depolarized Dynamic Light Scattering NMR Relaxation
2016/5/23
The dynamics of three synthetic oligonucleotides d(CG)4, d(CG)6, and d(CGCGTTGTTCGCG) of different length and shape were studied in solution by depolarized dynamic light scattering (DDLS) and time-res...
Fluorescence Lifetimes Measurements Using a Synchrotron Source
Fluorescence Lifetimes Measurements Synchrotron Source
2016/5/20
Fluorescence Lifetimes Measurements Using a Synchrotron Source.