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Healthy sleep may rely on long-overlooked brain cells(图)
Healthy sleep rely on long-overlooked jbrain cells
2021/4/9
For something we spend one-third of our lives doing, we still understand remarkably little about how sleep works -- for example, why can some people sleep deeply through any disturbance, while others ...
Scientists are homing in on what a healthy human microbiome looks like, mapping the normal bacteria that live in and on a human body. But what about a healthy plant microbiome?Is there even such a thi...

本周在美国波士顿举行的国际互联健康峰会上,国际个人互联健康联盟(PCHA)联盟执行主席Patty博士向我校生物工程学院钟代笛教授授予了“PCHA Healthy Longevity奖”,以表彰其在过去11年中为全球个人互联健康产业所做的贡献。这是国内专家首次获得该奖项。同期获奖的单位和个人还有:Roche公司的Horst Merkle先生、Philips、IPSOS Healthcare、Oran...
Randomized controlled trial on the impact of early-life intervention with bifidobacteria on the healthy infant fecal microbiota and metabolome
infant gut microbiota probiotics bifidobacteria breastfeeding 16S rRNA gene metabolomics
2018/11/20
Background: Early-life colonization of the intestinal tract is a dynamic process influenced by numerous factors. The impact of probiotic-supplemented infant formula on the composition and function of ...
Fecal concentrations of bacterially derived vitamin K forms are associated with gut microbiota composition but not plasma or fecal cytokine concentrations in healthy adults
vitamin K microbiome metabolomics menaquinones phylloquinone whole grain
2018/11/16
Background: Emerging evidence suggests novel roles for bacterially derived vitamin K forms known as menaquinones in health and disease, which may be attributable in part to anti-inflammatory effects. ...
Fecal concentrations of bacterially derived vitamin K forms are associated with gut microbiota composition but not plasma or fecal cytokine concentrations in healthy adults
vitamin K microbiome metabolomics menaquinones phylloquinone whole grain
2018/11/20
Background: Emerging evidence suggests novel roles for bacterially derived vitamin K forms known as menaquinones in health and disease, which may be attributable in part to anti-inflammatory effects. ...
What’s normal? Oligosaccharide concentrations and profiles in milk produced by healthy women vary geographically
breastfeeding carbohydrates human milk actation oligosaccharides
2018/11/13
Background: Human milk is a complex fluid comprised of myriad substances, with one of the most abundant substances being a group of complex carbohydrates referred to as human milk oligosaccharides (HM...
Substituting whole grains for refined grains in a 6-wk randomized trial favorably affects energy-balance metrics in healthy men and postmenopausal women
body fat body weight continuous glucose monitoring energy metabolism
2018/11/13
Background: The effect of whole grains on the regulation of energy balance remains controversial.
Objective: We aimed to determine the effects of substituting whole grains for refined grains, indepen...
Peripheral skeleton bone strength is positively correlated with total and dairy protein intakes in healthy postmenopausal women
bone fragility bone microstructure dairy products finite element analysis fracture risk HR-pQCT nutrition osteoporosis protein intake
2018/11/12
Background: Bone mineral content (BMC) and bone mineral density (BMD) are positively correlated with dietary protein intakes, which account for 1–8% of BMC and BMD variances. However, the relation bet...
Effects of supplementation with nondigestible carbohydrates on fecal calprotectin and on epigenetic regulation of SFRP1 expression in the large-bowel mucosa of healthy individuals
nondigestible carbohydrates colorectal cancer calprotectin Wnt signaling epigenetics
2018/11/12
Background: Hyperactive Wnt signaling is frequently observed in colorectal cancer. Higher intakes of dietary fiber [nondigestible carbohydrates (NDCs)] and the fermentation product butyrate are protec...
A micronutrient-fortified young-child formula improves the iron and vitamin D status of healthy young European children: a randomized, double-blind controlled trial
iron deficiency vitamin D deficiency cow milk young-child formula vitamin D supplements micronutrient fortification young children
2018/11/12
Background: Iron deficiency (ID) and vitamin D deficiency (VDD) are common among young European children because of low dietary intakes and low compliance to vitamin D supplementation policies. Milk i...
Protein ingestion acutely inhibits insulin-stimulated muscle carnitine uptake in healthy young men
doubly labeled water energy requirement resting energy expenditure short bowel syndrome total energy expenditure
2018/11/26
Background: Increasing skeletal muscle carnitine content represents an appealing intervention in conditions of perturbed lipid metabolism such as obesity and type 2 diabetes but requires chronic L-car...
Effect of weekly physical activity frequency on weight loss in healthy overweight and obese women attending a weight loss program: a randomized controlled trial
physical activity pattern obesity weight loss diet waist circumference cardiometabolic disease risk
2018/12/18
Background: The effect of intensity and duration of physical activity (PA) on weight loss has been well described. However, the effect of the frequency of weekly PA on weight loss is still unknown.
Prospective associations of maternal betaine status with offspring weight and body composition at birth: the Growing Up in Singapore Towards healthy Outcomes (GUSTO) cohort study
betaine pregnancy birth weight infants adiposity
2018/12/18
Background: Betaine supplementation results in lower body weight and fat mass and higher lean mass in animals and adult humans. However, the relation between maternal betaine status and offspring birt...
Intragastric administration of leucine or isoleucine lowers the blood glucose response to a mixed-nutrient drink by different mechanisms in healthy, lean volunteers
branched-chain amino acids energy intake food intake gastric emptying GIP GLP-1 glucagon gut hormones humans insulin
2018/12/18
Background: The branched-chain amino acids leucine and isoleucine lower blood glucose after oral glucose ingestion, and the intraduodenal infusion of leucine decreases energy intake in healthy, lean m...