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New research out of Case Western Reserve University School of Medicine describes a mechanism by which an essential quality control system in cells identifies and destroys faulty genetic material. The ...
Understanding how electric fields and their fluctuations in the active site of enzymes affect efficient catalysis represents a critical objective of biochemical research. We have directly measured the...
Heat shock transcription factor 1 (HSF1) is an evolutionarily conserved transcription factor that protects cells from protein-misfolding-induced stress and apoptosis. The mechanisms by which cytosolic...
A team led by researchers at UC Santa Cruz has developed chip-based technology for reliable detection of Ebola virus and other viral pathogens. The system uses direct optical detection of viral molecu...
Grid cells in the entorhinal cortex appear to represent spatial location via a triangular coordinate system. Such cells, which have been identified in rats, bats and monkeys, are believed to support a...
Ras homolog enriched in brain (Rheb) and FK506 binding protein 38 (FKBP38) are two important regulatory proteins in the mammalian target of rapamycin (mTOR) pathway. There are contradictory data on th...
Photoreceptors are a class of sensory neuronal cells that are deleteriously affected in many disorders and injuries of the visual system. Significant injury or loss of these cells often results in a p...
We analyze theoretically the effects of excluded-volume interactions between motors on the dynamics of a cargo driven by multiple motors. The model considered shares many commons with other recently p...
Genetic parameters of growth traits were estimated in the German Angora rabbit reared in the sub-temperate region of India. Estimates of (co)variance components were obtained for body weights at weani...
The dearth of general-use (i.e. quasi-‘universal’) primer sets for the amplification of single-copy nuclear DNA (scnDNA) loci, combined with the availability and ease of use of mitochondrial (mtDNA...
摘要利用16S~23S rDNA间区(intergenic spacer regions,ISR)在不同细菌中拷贝数、碱基排列、序列长度及所含tRNA基因种类和数目的差异,对15株链球菌和流感嗜血杆菌进行属、种、型和株系的分类鉴定。在16S rDNA的3′端和23S rDNA的5′端的保守区中合成引物,PCR扩增16S~23S rDNA ISR序列,对多态片段切胶纯化直接测序。在GenBank上查...
专著信息 书名 Third-generation biosensors based on direct electron transfer of proteins 语种 英文 撰写或编译 作者 Wenjun Zhang,Genxi Li 第一作者单位 出版社 Anal. Sci., in press,SCI源 (Invited review paper) 出版地 出版日期 年 月 日 标准书号 介...
期刊信息 篇名 Brain natiuretic peptide uncovers direct (endothelium-independent)relaxant and cyclic AMP responses to calcitonin gene-related peptide in rat aorta 语种 英文 撰写或编译 作者 Fiscus,R.R,L.Lu,A,W.K.Tu,H.Ha...
期刊信息 篇名 The direct electrochemistry of cytochrome b5 and its mutant protein 语种 英文 撰写或编译 撰写 作者 Yun-Hua Wang,Jun Cui,Yu-Long Sun,Ji-Hua Zhuan,Yi Xie,and Zhong Xian Huang 第一作者单位 刊物名称 J.Electronal. Chem. ...
Competitive direct ELISA was developed to detect gentamicin residues. Mice immunized with gentamicin-keyhole limpet hemocyanin (KLH) conjugate developed good antiserum titers, which gradually increase...

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