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Longitudinal study of alcohol consumption and HDL concentrations: a community-based study
alcohol cardiovascular disease risk epidemiology HDL lipids prospective cohort triglyceride
2018/11/13
Background: In cross-sectional studies and short-term clinical trials, it has been suggested that there is a positive dose-response relation between alcohol consumption and HDL concentrations. However...
氧化修饰HDL对培养人主动脉平滑肌细胞胆固醇流出的影响
High density lipoprotein Oxidative modification Cultured human smooth muscle cells Cholesterol efflux
2008/1/5
Intracellular accumulation of cholesterol in vascular wall cells is critical in atherosclerosis. HDL causes cholesterol effluxing from endothelial cells,macrophages and fibroblasts. To study the effec...
人动脉平滑肌细胞HDL受体酶联测定法
Human arterial smooth muscle cells HDL receptor Enzyme-linked method HRPHDL
2007/12/24
Using horseradish peroxidase (HRP)-HDL3, instead of the classical 125 I-HDL3, an enzyme linked assay for measuring HDL recptor on cultured human arterial smooth muscle cells (SMC )was developed. Horse...
化学发光法测定正常人皮肤纤维母细胞高密度脂蛋白(HDL)受体功能
细胞 高密度脂蛋白受体 化学发光
2007/12/21
摘要 用氨基丁基乙基异鲁米诺(ABEI)通过碳二亚胺(EDC)法标记分离的无载脂蛋白E的HDL_3。其标记率为0.89m mol/m mol HDL_3。HDL_3-ABEI与Apo A-Ⅰ和Apo A-Ⅱ抗体作用仍有免疫反应,说明标记后的HDL_3其免疫原性没有丧失。用HDL_3-ABEI与传代培养的正常人皮肤纤维母细胞作用,测其HDL受体活性。标记配基HDL_3-ABEI与人皮肤纤维母细胞HD...
摘要 动脉平滑肌细胞(SMC)是动脉粥样硬化(AS)斑块中的主要细胞,它的增殖在AS形成过程中极其重要。脂蛋白和氧化修饰型脂蛋白对SMC增殖的影响以及SMC增殖与原癌基因异常表达的关系是当前AS发病机制研究的热点之一。我们在建立人主动脉SMC体外培养方法的基础上,观察了LDL,VLDL及HDL和相应的氧化修饰型脂蛋白对培养人SMCfos,myc,erb-B原癌基因转录表达的影响。结果表明:①HDL...
北京鸭血清HDL主要载脂蛋白的高效液相层析分离及其理化性质
北京鸭 脂蛋白 分离
2007/12/7
摘要 用高效液相层析(HPLC)对北京鸭血清高密度脂蛋白(HDL)的所有载脂蛋白(apo)分离纯化,得五个主要apo峰,经SDS-PAGE鉴定,均为单一带;并做了IEF、糖基含量分析;对其中含量高的四个apo峰样进行了氨基酸组成测定和N-端部分氨基酸序列分析;从所做理化性质的研究,发现北京鸭血清HDL中的主要apo为:A-Ⅰ、C-Ⅲ_o、apoC-Ⅲ_s(s=1,2)、apoC's及可能的A-Ⅲ,...
Increase in Plasma HDL-Cholesterol Concentration in Goats Fed Sesame Meal Is Related to Ether Extract Fraction Included in the Meal
Sesame Meal Sesame Oil HDL-Cholesterol Goats
2016/4/13
Previously, we reported that a diet including sesame meal (SM) increased plasma total and high-density lipoprotein (HDL)-cholesterol concentrations in goats. In the present study, the components in th...
Dietary Sesame Meal Increases Plasma HDL-cholesterol Concentration in Goats
Sesame Meal Plasma HDL-cholesterol Goats
2016/4/12
Influence of dietary sesame meal on plasma glucose, non-esterified fatty acid (NEFA), triglyceride, total cholesterol, high-density lipoprotein (HDL)-cholesterol and urea concentrations in goats was e...