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GFP Variants with Alternative β‑Strands and Their Application as Light-driven Protease Sensors:A Tale of Two Tails
Green Fluorescent Proteins Peptide Hydrolases Light
2016/5/25
Green fluorescent protein (GFP) variants that carry one extra strand 10 (s10) were created and characterized, and their possible applications were explored. These proteins can fold with either one or ...
ONTOLOGY-DRIVEN AND NETWORK–ENABLED SYSTEMS BIOLOGY CASE STUDIES
bioinformatics Integration of genomics
2015/5/27
With the progress in high-throughput technologies and bioinformatics in recent years, it is possible to determine to what extent genetic or environmental manipulation of a biological system affects th...
Electrostatically Driven Aggregation of B-Lactoglobulin (BLG) and Effects of Added Polyelectrolytes
electrostatically driven aggregation polyelectrolytes B-Lactoglobulin
2015/5/27
The aggregation rate of B-Lactoglobulin (BLG) was studied using turbidimetry and dynamic light scattering in the range 5.8rength of 4.5 mM, and in the range 4.5 - 500mM NACl...
Evidence of an Infectious Asthma Phenotype: Chlamydia Driven Allergy and Airway Hyperresponsiveness in Pediatric Asthma
allergy asthma atopy chlamydia hyperresponsivness
2015/1/28
Asthma is the most common chronic respiratory disease affecting young children and adults all over the world. An estimated 34.1 million Americans have reported asthma in their lifetime and the disease...
A New Laser Pointer Driven Optical Microheater for Precise Local Heat Shock
heat shock optical fibers fate map hsp70 promoter pituitary lineage tracing
2014/12/12
The zebrafish has emerged as an important genetic model system for the study of vertebrate development. However, while genetics is a powerful tool for the study of early gene functions, the approach i...
To kill or not to kill: The balance between lytic and lysogenic viral infection is driven by trophic status
The balance lytic lysogenic viral infection trophic status
2014/4/2
Experiments were conducted to investigate spatiotemporal patterns in lytic and lysogenic viral infection using water samples collected on the Canadian Arctic Shelf, southern Beaufort Sea. Viral produc...
Ecosystem model reveals why women are driven out of science
Ecosystem model driven out of science
2014/7/16
Understanding how a species battles to sustain itself in a challenging habitat is a cornerstone of ecological research.
Modelling of light driven CO2 concentration gradient and photosynthetic carbon assimilation flux distribution at the chloroplast level
photosynthesis chloroplast CO2 flux Calvin cycle limiting factors
2012/5/3
The steady state of the two-substance model of light driven carbon turnover for the photosynthetic CO2 assimilation rate is presented. The model is based on the nonlinear diffusion equation for a sing...
Tensegrity and Motor-Driven Effective Interactions in a Model Cytoskeleton
Tensegrity Motor-Driven Effective Interactions Model Cytoskeleton Biological Physics
2012/4/24
Actomyosin networks are major structural components of the cell. They provide mechanical integrity and allow dynamic remodeling of eukaryotic cells, self-organizing into the diverse patterns essential...
Translocation of a polymer chain driven by a dichotomous noise
Translocation polymer chain driven dichotomous noise
2012/2/28
We consider the translocation of a one-dimensional polymer through a pore channel helped by a motor driven by a dichotomous noise with time exponential correlation. We are interested in the study of t...
An acoustically-driven biochip - Impact of flow on the cell-association of targeted drug carriers
acoustically-driven biochip - Impact flow cell-association targeted drug carriers
2011/8/11
Abstract: The interaction of targeted drug carriers with epithelial and endothelial barriers in vivo is largely determined by the dynamics of the body fluids. To simulate these conditions in binding a...
Heat Dissipation and Nonequilibrium Thermodynamics of Quasi-Steady States and Open Driven Steady State
Heat Dissipation Nonequilibrium Thermodynamics Quasi-Steady States Open Driven Steady State
2011/9/13
We develop a comparative thermodynamic theory, based on master-equation description of driven chemical reactions, for quasi-steady-state (QSS) and open-system nonequilibrium steady-state (NESS) sustai...
SATELLITE DRIVEN ESTIMATION OF PRIMARY PRODUCTIVITY OF AGROECOSYSTEMS IN INDIA
Earth observation ecosystem modeling gross primary productivity SPOT-VEGETATION agro-ecosystem
2014/5/6
Earth observation driven ecosystem modeling have played a major role in estimation of carbon budget components such as gross primary productivity (GPP) and net primary production (NPP) over terrestria...
The perfect integrator driven by Poisson input and its approximation in the diffusion limit
perfect integrator driven Poisson input approximation diffusion limit
2010/11/15
In this note we consider the perfect integrator driven by Poisson process input. We derive its equilibrium and response properties and contrast them to the approximations obtained by applying the diff...
A sparse regulatory network of copy-number driven expression reveals putative breast cancer oncogenes
twork copy-number driven expression reveals putative breast cancer oncogenes
2010/11/15
The influence of DNA cis-regulatory elements on a gene's expression has been intensively studied. However, little is known about expressions driven by trans-acting DNA hotspots. DNA hotspots harboring...