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一种抗人PrPC蛋白的单克隆抗体,能够以靶向方式降低转录因子Twist1的表达水平,并诱导巨噬细胞和NK细胞靶向直肠癌肿瘤细胞。 抗体与西妥昔单抗联合用药的抑瘤效果也优于单用抗体或西妥昔单抗。
延缓衰老,制备恶性人骨髓间充质干细胞的方法可抗选择性。 制备方法, 第二密码子的253个氨基酸残基的FOXO3蛋白, 丝氨酸密码子编码丙氨酸突变的密码子,FOXO3蛋白密码子的第315位氨基酸残基,丝氨酸密码子编码丙氨酸突变的密码子编码2个突变中的一个突变,编码多能干细胞的基因组包括该步骤。 制备的重组间充质干细胞,并进一步提供其在移植治疗中的用途。 [附图]
Researchers at MIT and Harvard University have designed a way to selectively turn on gene therapies in target cells, including human cells. Their technology can detect specific messenger RNA sequences...
The Human Genome Project was an ambitious initiative to sequence every piece of human DNA. The project drew together collaborators from research institutions around the world, including MIT's Whitehea...
“We have been interested in the romantic life of the parasite Cryptosporidium for some time,” says Boris Striepen, a scientist in Penn’s School of Veterinary Medicine.
To the human eye, most stationary objects appear to be just that — still, and completely at rest. Yet if we were handed a quantum lens, allowing us to see objects at the scale of individual atoms, wha...
Every time we reach for a cup, our brains must assess our hands’ current position in relation to the mug and then command muscles to make the proper adjustments to successfully grab the handle.
26 April 2007,Oxford scientists have for the first time revealed a link between a gene and the activity of human stem cells, giving hope that stem cell transplant success for blood cancer patients may...
4-Apr-2007,BLOOMINGTON, Ind. -- For the first time, scientists from the University of Washington School of Medicine, Indiana University Bloomington and the University of Cambridge have determined how ...
06 February 2007,By tweaking these dual role regions, scientists could develop gene therapy techniques that produce proteins that are even better than those found in nature, and could one day be used ...
February 6, 2007,WASHINGTON - Researchers on a safari for microbes have found that human skin is populated by a veritable menagerie of bacteria - 182 species - some apparently living there permanently...
February 2, 2007,Today's release of a widely anticipated international report on global warming coincides with a growing clamor within the United States to reduce greenhouse gas emissions and prevent ...
Dec. 1, 2006,LAWRENCE — University of Kansas researchers are learning a lot about humans from a tiny roundworm.Researchers commonly use the worm, Caenorhabditis elegans, or C. elegans, to study a rang...

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