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Inhibition of nitric oxide synthase on brain oxygenation in anesthetized rats exposed to hyperbaric oxygenhernia
HBO oxygen toxicity nitric oxide drug hyperbaric nitric oxide synthase animal rat
2009/6/9
Nitric oxide (NO) production is involved in the development of oxygen toxicity of the central nervous system (CNS) since inhibition of nitric oxide synthase (NOS) significantly protects animals from h...
Reversibility in blood-brain barrier, microcirculation, and histology in rat brain after decompression
decompressio air animal rat
2009/6/8
To examine the changes in blood-brain barrier (BBB), cerebral microcirculation, and histology from 15 min to 72 h after decompression, 90 rats were exposed to experimental compression to 6 atm abs air...
Attenuation of brain hyperbaric oxygen toxicity by fasting is not related to ketosis
seizure hyperbaric rat animal
2009/6/8
The effect of 24 h of fasting and changes in blood glucose and beta-hydroxybutyrate (BHB) level on latency to seizures in hyperbaric oxygen (HBO2) was studied. Conscious, unrestrained rats implanted w...
Effect of anti-C5a antibody on blood-lung and blood-brain barrier in rabbits after decompression
decompression pulmonary complement rabbit animal
2009/6/8
The complement activation product C5a may be an important mediator of tissue injury after decompression stress. This study investigated whether the administration of anti-C5a antibody may reduce chang...
Voluntary breath holding affects spontaneous brain activity measured by magnetoencephalography
breath hold magnetoencephalography brain
2009/6/8
Spontaneous brain activity was measured by multichannel magnetoencephalography (MEG) during voluntary breath holds. Significant changes in the activity are limited to the alpha rhythm: 0.25 Hz frequen...
The effect of air bubbles on rabbit blood brain barrier
animal Rabbit Blood-Brain Barrier drug effects Brain drug effects
2009/6/5
Several investigators have claimed that the blood brain barrier (BBB) may be broken by circulating bubbles, resulting in brain tissue edema. The aim of this study was to examine the effect of air bubb...
Hyperbaric oxygenation affects rat brain function after carbon monoxide exposure
Animal rat Brain metabolism Carbon Monoxide Poisoning Hyperbaric Oxygenation
2009/6/5
The application of hyperbaric oxygenation (HBO2) has been recommended for correction of neurological injury in severely CO-poisoned patients. However, the mechanisms of HBO2 action on brain mitochondr...
I am a neurosurgeon and will discuss the clinical use of hyperbaric oxygen therapy (HBO2) on the central nervous system, especially the brain. Is there a role for HBO2 in brain injury? This is not an ...
Effect of 2.1 MPa and 4.1 MPa H2O2 exposure on auditory brain stem evoked potential in mice
Decompression methods Animal Evoked Potentials Auditory Brain Stem
2009/6/2
Brain auditory evoked potential (BAEP) in mice exposed to hyperbaric H2O2 pressure was monitored to reveal the correlation between altered synaptic transmission and hydrogen narcosis or isobaric HPNS....
Voltage sensitive dye imaging of transient neuronal assemblies in brain slices under hyperbaric conditions
voltage sensitive dye pressure-reversal Brain slices animal rat
2009/6/2
We have developed a high pressure optical cell to study large-scale transient neuronal coalitions--"assemblies" using voltage sensitive dye (VSD) fluorescence combined with fast CCD imaging of brain s...
Carbon monoxide: From toxic poison to brain messenger
Carbon Monoxide Carbon Monoxide Poisoning Carboxyhaemoglobin haemoproteins lipid peroxidation Cytochrome C surface absorption immune suppression nitric oxide review
2009/5/26
Introduction
Carbon monoxide (CO) is the most common lethal
poison in every community that has been studied.1
Although many of these poisonings are the result of a
deliberate exposure to commit a ...
Failure of normobaric oxygen therapy to reduce ischemic brain damage in rats
outcome sischemic brain damage animal rat
2009/3/28
We investigated the effects of 24-h oxygen therapy on focal cerebral ischemia in rats. Under halothane anesthesia, a 3-0 nylon thread was introduced into the neck internal carotid artery to occlude th...
Relationship between the event-related brain potential P300 and inert gas narcosis
narcosis cognitive inert gas narcosis
2009/3/28
It is known that inert gas narcosis slows both reaction time (RT) and the event-related brain potential P300 in a correlated and dose-dependent manner. On the assumption that P300 reflects the time to...
Microbubble damage to the blood-brain barrier: relevance to decompression sickness
decompression pulmonary blood brain barrier bubbles animal Guinea Pigs
2009/3/25
Decompression sickness affecting the nervous system is still a serious problem in diving, but the mechanisms involved are in dispute. Although microbubbles can be detected in the pulmonary artery on ...