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Endothelial Dysfunction in Erectile Dysfunction：Role of the Endothelium in Erectile Physiology and Disease
Endothelial Dysfunction Erectile Dysfunction Endothelium Erectile Physiology Disease
2008/12/19
Erectile dysfunction (ED) is defined as the consistent inability to obtain or maintain an erection for satisfactory sexual intercourse. Basic science research on erectile physiology has been devoted t...
A Castrated Mouse Model of Erectile Dysfunction
Penile erection castration penis androgen testosterone animal model
2008/12/19
To establish a mouse model for the study of venoocclusive erectile dysfunction, we investigated erectile function in wild-type (WT), castrated (CAST), and castrated mice receiving immediate testoste...
Challenges in Oral Therapy for Erectile Dysfunction
Challenges Oral Therapy Erectile Dysfunction
2008/12/15
Erectile dysfunction (ED) is the persistent inability to attain or maintain a penile erection sufficient to permit satisfactory sexual intercourse (NIH Consensus Conference, 1993). It is a highly prev...
K Channels as Molecular Targets for the Treatment of Erectile Dysfunction
K Channels Molecular Targets Treatment Erectile Dysfunction
2008/12/15
Normal erectile function is a complex neurovascular process that is dependent on a delicate balance between the effects of endogenous vasoconstrictor and vasorelaxing agents on the arterial and corpor...
K Channels as Molecular Targets for the Treatment of Erectile Dysfunction
K Channels Molecular Targets Treatment Erectile Dysfunction
2008/12/15
Normal erectile function is a complex neurovascular process that is dependent on a delicate balance between the effects of endogenous vasoconstrictor and vasorelaxing agents on the arterial and corpor...
Inhibition of Tonic Contraction—A Novel Way to Approach Erectile Dysfunction?
Inhibition Tonic Contraction Erectile Dysfunction
2008/12/15
Experiments from this laboratory have demonstrated that vasoconstriction in the cavernosal circulation is mediated, in part, by the RhoA/Rho-kinase calcium-sensitization pathway. When RhoA/Rho-kinase ...
Environmental Agents and Erectile Dysfunction: A Study in a Consulting Population
Argentina environment pesticides solvents
2008/12/5
We evaluated chemical and physical environmental agents as risk factors for erectile dysfunction among a consulting population. We studied 199 men who sought medical help for erectile disorders betw...
Pilot study of the endothelin-A receptor selective antagonist BMS-193884 for the treatment of erectile dysfunction
Pilot study endothelin-A receptor treatment erectile dysfunction
2008/12/1
Endothelins have been postulated to be important regulators of penile erectile function. The endothelin-A receptor antagonist BMS-193884 was evaluated as a treatment for mild-to-moderate erectile dysf...