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Skeletal response of growing rats to continuous long-term hyperbaric helium-oxygen exposure
hyperbaric Skeletal animal rat heliox
2009/7/20
Bone growth and composition were studied in growing rats following continuous long-term hyperbaric exposure. Six groups of eight rats each were maintained at 21 ATA He-O2 (200 mm Hg O2) and six groups...
Pressure-reduction limits for rats following steady-state exposures between 6 and 60 ATA
rat animal Decompression Sickness Pressure-reduction
2009/7/20
The role of pressure reduction in the formation and growth of bubbles is universally recognized and its significance in decompression theory has been accepted. Yet the allowable limits of pressure red...
Alteration of high pressure nervous syndrome in rats by alteration of colonic temperature
nervous syndrome colonic temperature Animal
2009/7/20
The components of the high pressure nervous syndrome (HPNS) have been clearly described previously. Animal studies of HPNS, however, have been characterized by nonstandardized definitions of the vario...
Reversal of nitrogen narcosis in rats by helium pressure
nitrogen narcosis nitrogen helium animal rat
2009/7/20
Changes in operant behavior were obtained for rats breathing nitrogen, helium, and both gases combined. Exposure to 12.9 ATA of nitrogen (O2 maintained at normobaric value of 0.2 ATA) produced complet...
Dive-induced modifications in platelet kinetics in rats
decompression platelet kinetics rat animal
2009/7/20
The effect of a simulated dive to 8 ATA on platelet kinetics was studied in normal and splenectomized male and normal female rats. Platelet production and consumption was measured in vivo 1 h and 1 da...
Cerebellar and cerebral electroencephalogram during the high pressure nervous syndrome (HPNS) in rats
high pressure nervous syndrome electroencephalogram animal rat seizures
2009/7/20
Electroencephalographic activity of the frontal cortex, cerebellar vermis, and superior vestibular nucleus was recorded in awake rats during the high pressure nervous syndrome (HPNS) by means of perma...
Effect of long-term hyperbaric He-O2 exposure on the weight and histology of endocrine organs in growing rats
heliox oxygen toxicity endocrine animal rat
2009/7/20
The effects of long-term hyperbaric exposure on endocrine organ weight and histology and on epiphyseal-plate width were studied in growing male rats. Six groups of rats were exposed to 21 ATA He-O2 (2...
Effects of hyperbaric helium-oxygen on the antipyretic actions of aspirin and acetaminophen in rats
hyperbaric animal rat drug antipyretic aspirin acetaminophen heliox
2009/7/20
The effects of two antipyretics, aspirin and acetaminophen, were studied under hyperbaric helium-oxygen conditions. Groups of yeast-fevered rats were given three different doses of each antipyretic in...
Effect of cerebellar ablation on the high pressure nervous syndrome in rats
high pressure nervous syndrome cerebellar ablation animal rat seizures
2009/7/17
To evaluate the interaction between high pressure nervous syndrome (HPNS) seizures and cerebellar integrity, seizure threshold pressure (Pc) of normal rats was compared with that of rats sustaining ce...
Testicular blood flow and plasma testosterone concentrations in anesthetized rats previously exposed to air at 6 ATA
plasma testosterone animal rat air Testicular
2009/7/17
Testicular blood flow and peripheral testosterone levels were measured in sodium pentobarbitone anesthetized adult rats within 3 h of exposure to air at 6 ATA for 24 h. The animals appeared clinically...
Reduction of the incidence of decompression sickness in rats by smooth-muscle activating factor (SMAF)
decompression
2009/7/17
Normal rats were injected with a smooth-muscle activating factor (SMAF) to examine the dose-response relationshio of SMAF to the incidence of decompression sickness. After injections of saline or 1.0,...
Effect of helium/nitrogen/oxygen mixtures on HPNS convulsion threshold in euthermic rats
high pressure nervous syndrome trimix convulsion animal rat seizures heliox
2009/7/17
This study compares the effects of various so-called trimix mixtures (10, 20, and 40 percent N2 in He-O2) on the convulsion threshold pressure (Pc) and EEG activity in 60 adult male Wistar rats with c...
Therapeutic effects of hyperbaric oxygen and dimethyl sulfoxide following spinal cord transections in rats
Gelderd,JB Welch,DW Fife,WP Bowers,DE
2009/7/17
Thirty adult, male, Long-Evans hooded rats underwent spinal cord transections at the T5 vertebral level. Following surgery, animals were separated into three groups: Group I received only normal posto...
In vitro and in vivo studies have shown that pressure treatment before decompression reduces bubble formation. This has been interpreted as evidence that bubbles originate from pre-existing gas nuclei...
Phospholipid synthesis in isolated perfused lungs of rats made tolerant to 100% oxygen
pulmonary Phospholipid synthesis lung oxygen animal rat
2009/7/16
Tolerance to 100percent oxygen is readily induced in the rat by prior exposure to 80percent oxygen for 7 days. In order to determine whether the rate of synthesis, or te alveolar content, of pulmonary...