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Enrichment Discrimination Behavior in Spontaneously Hypertensive Rats
Attention Deficit Enrichment Discrimination Spontaneously Hypertensive Rat Atomoxetine
2013/1/29
Objectives: 1) To reveal, among spontaneously hypertensive rats, subpopulations that diverge in attention to objects enriching an empty cross-maze; 2) To evaluate effect of clinically efficient drug f...
5-HT2A Receptor Activation Normalizes Exaggerated Fear Behavior in p-Chlorophenylalanine (PCPA)-Treated Rats
Fear Conditioning Startle Reflex 5-HT2 DOI Ketanserin SB 206553
2013/1/29
Deficits in serotonin (5-hydroxytryptamine, 5-HT) neurotransmission are implicated in abnormal emotional behaviors such as aggression, anxiety, and depression. However, the specific 5-HT receptor mech...
Comparative pharmacokinetics of cefuroxime lysine after single intravenous, intraperitoneal, and intramuscular administration to rats
cefuroxime lysine intravenous administration intramuscular administration intraperitoneal administration pharmacokinetics
2012/11/20
Aim: To compare the pharmacokinetic parameters of cefuroxime lysine, a new second-generation of cephalosporin antibiotics, after intravenous (IV), intraperitoneal (IP), or intramuscular (IM) administ...
Oral bioavailability and intestinal disposition of dehydroandrographolide in rats
脱水穿心莲内酯 药代动力学 肠道处置 Caco-2细胞 大鼠在体肠灌流
2012/8/20
目的研究脱水穿心莲内酯在大鼠体内的口服生物利用度和肠道处置，为其在临床的使用和开发提供有用的信息。方法研究脱水穿心莲内酯在大鼠体内的药代动力学行为。采用Caco-2细胞模型和大鼠在体肠灌流模型研究脱水穿心莲内酯在大鼠体内的肠道处置。结果脱水穿心莲内酯的口服绝对生物利用度是11.92%。在Caco-2细胞模型中，脱水穿心莲内酯从基底膜到顶端膜方向转运的表观渗透系数（5.37×10-5 cm/s）约等...
The Effect of Egg Yolk Oil in the Healing of Third Degree Burn Wound in Rats
Burn Egg yolk Wound Silver sulfadiazine Rat
2015/9/24
Background: Burn injury is a major cause of death and dis-ability worldwide. A domestic medication in wound healing, preventing infection and reduction of scar tissue as well as availability is still ...
The Effect of Tomato and Tomato Paste Supplementation on the Serum Lipids and Lipoproteins Levels in Rats Fed with High Cholesterol Diet
Hypercholesterolemia Lipid Lipoprotein Tomato Rat
2015/9/24
Background: Scientists have shown that consumption of antioxidants can reduce hypercholesterolemia including fruit and vegetables. This study aims to compare the effect of tomato and tomato paste supp...
A Comparison between the Efficacy of Iranian and Syrian Hydrogel Dressings on Wound Healing in Rats
Hydrogel Dressing Wound healing Iran Syria Rat
2015/9/23
Background: Following the production of Syrian gel, the scientists from Atomic Energy Commission of Syria, in cooperation with researchers in Yazd Atomic Energy Commission Radiation Processing Center ...
Vitamin C modulates oxidative stress-induced colitis in rats
Vitamin C colitis histopathology oxidative stressrats
2010/12/21
Free radicals are an important factor in the etiopathogenesis of colitis and may increase oxidative damage. The antioxidant vitamin C efficiently scavenges free oxygen radicals. The present study aime...
Vitamin C modulates oxidative stress-induced colitis in rats
Vitamin C colitis histopathology oxidative stress rats
2010/11/22
Free radicals are an important factor in the etiopathogenesis of colitis and may increase oxidative damage. The antioxidant vitamin C efficiently scavenges free oxygen radicals. The present study aime...
The Effects of Aqueous Extract of Vaccinium Arctostaphylos Leaves on Blood Pressure in Renal Hypertensive Rats
Vaccinium arctostaphylos Rat Blood pressure Hypertension
2015/9/22
Background: The leaves of Vaccinium arctostaphylos (Qare qat) is advocated for the treatment of hypertension in Iran' folk medicine. The objective of was to examine the possible hypotensive activity o...
Effects of alendronate and risedronate therapy on hepatic antioxidant enzyme activity and lipid peroxidation in ovariectomized rats
Alendronate risedronate ovariectomy antioxidants
2010/10/14
To evaluate the effects of alendronate (ALN) and risedronate (RIS), which are agents for preventing and treating postmenopausal osteoporosis, on hepatic antioxidant enzyme activity and lipid peroxidat...
Hypolipidemic and antioxidant activity of aqueous extract of Monascus purpureus fermented Indian rice in high cholesterol diet fed rats
Hypolipidemic, antioxidant lipid peroxidation DPPH
2011/3/22
To evaluate hypolipidemic and anti-oxidant activities of Monascus purpureus fermented Indian variety of rice. Materials and methods: Indian rice variety IR-532-E-576 was fermented with Monascus purpur...
Effects of 50 Hz electric field on malondyaldehide and nitric oxide levels in spinal cord of rats at prenatal plus postnatal period
Electric field oxidative stress nitric oxide malondialdehyde spinal cord
2011/3/22
The effect of 50 Hz electric field (EF) on developing neural tissues is not known. We aimed to determine whether there would be any oxidative stress effect of 50 Hz EF on developing spinal cord tissu...
Ethanol Upregulates iNOS Expression in Colon Through Activation of Nuclear Factor-kappa B in Rats
Colon Motility iNOS NF-jB Ethanol
2014/5/16
Background: Alcohol inhibits colonic motility but the mechanism is unknown. The goal of this study was to test the possibility that nuclear factor-kappa B (NF-jB) is involved in the upregulation of in...
Low-Intensity Pulsed Ultrasound Stimulation of Condylar Growth in Rats
Ultrasound stimulation Mandibular growth
2010/3/8
Objective: To test the hypothesis that low-intensity pulsed ultrasound (LIPUS) stimulation does not histologically affect the growth of mandibular condylar cartilage.
Materials and Methods: Thirty-fi...