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Mild hypothermia induces apoptosis in rat testis at specific stages of the seminiferous epithelium
Cell death spermatogenesis ferti
2009/2/17
This study was designed to determine the effects of short episodes of mild hypothermia on cell apoptosis in the testis of the adult rat. Apoptosis was assessed by in situ DNA 3'-end labeling in the ...
The effects of gonadotropin-releasing hormone immunization and recombinant follicle-stimulating hormone on the Leydig cell and macrophage populations of the adult rat testis
Stereology morphometry optical disector leucocytes
2009/2/17
The objective of this study was to investigate the role of the gonadotropins and, in particular follicle-stimulating hormone (FSH) in maintaining the Leydig cell and macrophage populations of the adul...
Low density lipoprotein receptor-related protein-1 expression in the testis：regulated expression in Sertoli cells
protein-1 testis regulated expression Sertoli cells
2009/2/17
The low density lipoprotein receptor-related protein (LRP-1) is a multiligand receptor capable of mediating endocytosis of a wide array of ligands that relate to both lipoprotein metabolism and pr...
Differential methylation in steroid 5 alpha-reductase isozyme genes in epididymis, testis, and liver of the adult rat
Gene methylation gene expression androgens dihydrotestosterone eukaryotic adenine methylation
2009/2/17
DNA methylation has been largely involved in the regulation of tissue-specific gene expression. The aim of the study was to determine the methylation pattern of steroid 5 alpha-reductase genes 1 and 2...
Effects of a 5 alpha-reductase inhibitor, finasteride, on the developing prostate and testis of a marsupial
Virilization Wolifian duct tammar wallaby androgen dihydrotestosterone
2009/2/17
This study examines the role of dihydrotestosterone in virilization of the developing male tammar. The onset of prostate differentiation in this marsupial species normally occurs around 25 days po...
Characterization and developmental expression of a testis-specific adenosine deaminase mRNA in the mouse
testis-specific adenosine deaminase mRNA mouse
2009/2/17
Adenosine is able to alter intracellular cAMP levels and to affect the physiological functions of sperm. It also modulates FSH action through its Gi protein coupled receptors. Adenosine deaminase (A...
Comparison of the response of rat testis and accessory sex organs to treatment with testosterone and the synthetic androgen methyltrienolone（R1881）
Androgens spermatogenesis testis prostate
2009/2/17
We have studied the ability of the synthetic androgen methyltrienolone (R1881) to maintain testis and accessory organ weights, as compared to the effect of testosterone propionate (TP). In contrast ...
Expression of apolipoprotein E mRNA in the epithelium and interstitium of the testis and the epididymis
Apolipoprotein E mRNA Leydig cells Sertoli cells
2009/2/17
Apolipoprotein E (apo E) is an important constituent of plasma lipoproteins and is believed to be involved in the regulation of lipid transport and distribution between tissues. The production of ...
Isolation of highly purified type A spermatogonia from prepubertal rat testis
Type A spermatogonia cell separation c-kit cell culture
2009/2/17
We have developed a new method that allows isolation of highly purified type A spermatogonia from prepubertal rats. The procedure is based on the maximal release of spermatogonia from the seminifero...
Pituitary control of proliferation and differentiation of Leydig cells and their putative precursors in immature hypophysectomized rat testis
Testis rat development Leydig cells steroidogenesis
2009/2/17
The objective of this study was to determine the effects of pituitary hormones (luteinizing hormone [LH], follicle-stimulating hormone [FSH], growth hormone [GH], and prolactin [PRL]) on interstit...
Ultrastructural observations of spermatogenesis following transplantation of rat testis cells into mouse seminiferous tubules
Testis spermatogenesis transplant rat mouse
2009/2/17
The testes of busulfan-treated immunodeficient mice receiving seminiferous tubule injections of testis cells from rats were examined by light and electron microscopy. The presence of active rat sper...
Differential expression of clusterin in the testis and epididymis of postnatal and germ cell deficient mice
clusterin epididymis postnatal germ cell deficient mice
2009/2/16
Clusterin is found in a wide variety of tissues and is expressed in a number of physiological and pathological contexts. It is expressed constitutively in the adult male reproductive tract, specific...
Testosterone autoregulation of its biosynthesis in the rat testis：inhibition of 17 alpha-hydroxylase activity
1 7a-Hydroxylase testosterone autoregulation rat
2009/2/16
Using the in vitro perfused rat testis, the effects of testosterone (T) on its own biosynthesis, and in particular on the inhibition of specific steroidogenic step(s) in the biosynthetic pathway fro...
Monoaminergic and peptidergic contributions of the superior and the inferior spermatic nerves to the innervation of the testis in the rat
Testicular capsule mesorchium protein gene product9.5 vasoactive intestinal peptide
2009/2/13
Sections of the rat testis and whole-mounts of the testicular capsule were studied microscopically using the glyoxylic acid-induced fluorescence method, to detect monoamines, and immunohistochemical...
We have previously found the presence of endothelin (ET) receptor and ET-like immunoreactivity in rat testis. We now extend our studies from rat to human testis. We found expression of a specific tr...