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Differentiation of Stem/ Progenitor Cells towards Vascular Cells by Mechanical Forces
Effect of Local Environment on Differentiation of Calcified Tissue Forming Cells.
For application of a cultured muscle to medical engineering, both to control C2C12 myoblast differentiation and to investigate a contraction mechanism of C2C12 myotube are important. The muscle can be...
Tissue inhibitor of metalloproteinases-1 (TIMP-1) and TIMP-2, originally known as intrinsic inhibitors of matrix metalloproteinases (MMPs), are now known as constitutive components in serum and have ...
The periodontal ligament is exposed to mechanical stress such as occlusion, so periodontal ligament cells may have defenses against mechanical stress. We searched for the influence of mechanical stres...
Vascular endothelial growth factor (VEGF) induces osteoclast differentiation as well as neovascularization by binding to the fms-like tyrosine kinase (Flt)-1 and fetal liver kinase (Flk)-1 receptors...
Evaluation of immunosuppressive tumor-escape mechanisms in tumor-bearing hosts is of great importance for the development of an efficient tumor immunotherapy. We document here the functional charact...
To examine the effects of the tat and nef regulatory genes of human immunodeficiency virus (HIV-1) on cell differentiation we used the mouse embryonic stem cells (ESC) as a model. Proliferation, embry...
To evaluate the biological functions of myogenic regulatory factors, we have examined the effects of ectopic expression of MyoD and Cx43 genes in the fibroblasts on the differentiation of myoblast in ...
The main treatment of leukemia is traditional radiochemotherapy, which is associated with serious side effects. In the past twenty years, differentiation was found as an important effective measure to...
Differentiation of Functional and Structural Dental Malocclusion and its Implication to Treatment.
We examined the role of hepatocyte growth factor (HGF) in the chondrogenesis and endochondral ossification in the forelimbs of mouse embryos by use of immunohistochemistry and organ culture system. ...
In this study we tried to identify new genes or proteins in skeletal muscle induced by exercise. We analyzed alterations of protein expression in mouse gastrocnemius muscles induced by swimexercise ...
Connexin (Cx) 43-mediated gap-junctional intercellular communication (GJC) mainly regulates the osteoblastic differentiation, but much of the function of Cx43 on the differentiation of bone marrow cel...
Changes in the expression of hyperpolarization-activated cyclic nucleotide (HCN)-gated channels and If currents during the differentiation of embryonic stem cells into cardiac cells remain unknown. ...

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