搜索结果: 46-60 共查到“理学 structural”相关记录321条 . 查询时间(0.062 秒)
Quantifying the model structural error in carbon cycle data assimilation systems
Quantifying the model structural error carbon cycle data assimilation systems
2014/12/17
This study explores the impact of the structural error of biosphere models when assimilating net ecosystem exchange (NEE) measurements or CO2 concentration measurements to optimise uncertain model par...
Structural changes between signaling states of bacterial chemoreceptors probed by solid -state NMR and hydrogen exchange
Structure of membrane protein lipid environment membrane signals bacteria chemical sensors membrane domains solid-state nuclear magnetic resonance (NMR)
2014/12/11
The limitations of structural studies of membrane proteins imposed by the lipid environment has made it difficult to determine the molecular mechanism of transmembrane signaling. For the bacterial che...
Structural and functional characterization of the unique N-terminus of Cse4p, A histone H3 -like protein at the S. cerevisiae centromere
Budding yeast the yeast protein protein fission yeast etc
2014/12/11
The budding yeast (S. cerevisiae) centromere component, Cse4p is an evolutionarily conserved histone H3-like protein, with homologues identified in fission yeast, worm, fly and human. All histone H3-l...
The ubiquitin E3 ligase Human Homolog of Drosophila Ariadne-1 (HHARI) is a structural and functional homolog of Parkin and is required for myogenesis
Autosomal genes Parkinson's disease human beings parkinsonism E3 ubiquitin ligase neurons dopaminergic neurons
2014/12/11
Several genes implicated in Parkinson's disease (PD) encode components of the ubiquitin-proteasome pathway. In a specific form of PD (human Autosomal Recessive Juvenile Parkinsonism, AR-JP), loss of f...
Functional tests of structural models for abortive cycling in T7 RNA polymerase
Pure sciences Biological sciences Abortive cycling RNA polymerase Transcription
2014/12/10
Transcription initiates when the enzyme binds to the promoter region and melts open an initial transcribing bubble that extends from position -4 to +4. The initiation phase continues until the enzyme ...
Structural studies of membrane-assembled PopD and PopB, the Pseudomonas aeruginosa type 3 secretion translocators
Pure sciences Biological sciences Fluorescence Membrane proteins Membranes Pore formation Type III secretion
2014/12/10
Transport of proteins across membranes is essential during many stages of pathogen infection and colonization of human cells. Many Gram-negative pathogens use a Type 3 Secretion (T3S) system to inject...
Structural And Biochemical Studies Of The Human Lysosomal Enzymes: N-Acetylgalactosamine-6-Sulfatase, N-Sulfoglucosamine Sulfohydrolase And Beta-Galactosidase
Pure sciences Biological sciences Cysteine modification Enzyme replacement therapy Lysosomal storage disease Pharmacological chaperone therapy Sulfatase structure X-ray crystallography
2014/12/10
Lysosomal storage diseases are disorders caused by deficiencies of enzymes responsible for the degradation of substances present in lysosomes. The loss of activity of a lysosomal enzyme leads to the a...
Structural Changes That Drive Timed Promoter Release In Transcription Reciprocally Lead To Abortive Instability
Biological sciences Aminopurine Abortive cycling Kinetics P266l Rna polymerase Transition Abortive instability
2014/12/10
RNA polymerases carry out a process, which at times carries contradictory mechanistic requirements. During initiation, an RNA polymerase should be highly sequence specific, binding only to and initiat...
STRUCTURAL BIOLOGY AND PHARMACOLOGY OF HUMAN CATHEPSIN A AND NEURAMINIDASE 1
Cathepsin A Neuraminidase Lysosomal storage diseases sialidosis Galactosialidosis serine carboxypeptidase
2014/12/10
Human cathepsin A (also known as Protective Protein/Cathepsin A, PPCA; E.C. 3.4.16.5) is a lysosomal serine carboxypeptidase. Cathepsin A is also involved in a complex with two other lysosomal enzymes...
Structural Analysis of Proteins by Covalent Labeling and Mass Spectrometric Detection
mass spectrometry protein 3D structure
2014/11/20
Covalent labeling and mass spectrometry are seeing increased use together as a way to obtain insight into the 3-dimensional structure of proteins and protein complexes. Several amino acid specific (e....
STRUCTURAL ANALYSIS OF THE TENSLEEP FAULT, BIGHORN BASIN, WYOMING (PALEOSTRESS, FORELAND, JOINTS)
Bighorn basin the Precambrian fault smooth surface rock rock
2014/10/22
The Tensleep Fault is an east-west trending Precambrian fault reactivated during the Laramide orogeny. This study of the fault west of the base of the Bighorn Mountains involves three levels of analys...
Numerical Modeling of Fracturing in Non-Cylindrical Folds: Case Studies in Fracture Prediction Using Structural Restoration
Fractures Geomechanics Joints Sant Corneli anticline Unfolding Fracture prediction Structural restoration
2014/10/22
This thesis contains several distinct studies aimed at better understanding fracturing in compressional fault-cored folds. At outcrops of growth strata in the Oliana anticline in the Spanish Pyrenees,...
Andean structural control on interseismic coupling in the North Chile subduction zone
Andean structural control interseismic coupling in the North Chile subduction zone
2014/4/9
Segmentation can influence the extent of earthquake rupture and event magnitude 1: large megathrust earthquakes result from total rupture of relatively continuous segments of the subduction interface ...
STRUCTURAL MONITORING WITH GEODETIC SURVEY OF QUADRIFOGLIO CONDOMINIUM (LECCE)
Monitoring Risk management Geomatic survey Data analysis Statistical test
2014/4/24
Monitoring buildings for moving elements has been always a problem of great importance for their conservation and preservation, as
well as for risk mitigation. In particular, topographic surveying a...
Analysis and Tectonic Implication of DEM-Derived Structural Lineaments, Sinai Peninsula, Egypt
Sinai Peninsula Structural Lineaments Statistical Analysis
2013/3/11
Sinai Peninsula has fascinating geologic setting and is displaying a diversity of structural lineaments that have greatly influenced the distribution of natural resources and hazards. Shaded relief im...