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近日,发表在《Nature Communications》上的一项新研究中,来自新加坡国立癌症中心、杜克-新加坡国立大学医学院等多家学术机构的联合研究团队发现了癌症如何逃避免疫系统后在体内转移的机制,并探索了抑制这一危险机制的可能性。该研究对开发癌症治疗的新策略具有重要意义。
Cancer drugs that stimulate the body’s immune system to attack tumors are a promising way to treat many types of cancer. However, some of these drugs produce too much systemic inflammation when delive...
目前,大多数临床策略仍依赖于肿瘤亚型的组织病理学分层,而对这些分层亚型中单细胞表型的空间位置信息知之甚少。加拿大麦吉尔大学研究团队绘制了肺肿瘤免疫微环境的单细胞空间图谱。该研究成果于近日发表在《Nature》杂志上,题为:Single-cell spatial landscapes of the lung tumour immune microenvironment。
Checkpoint inhibitor drugs have been a gamechanger for many cancer patients. Yet around 70% don’t respond to these medications, which work by removing the “brakes” on the immune system’s response to a...
Fibrosis is the thickening of various tissues caused by the deposition of fibrillar extracellular matrix (ECM) in tissues and organs as part of the body’s wound healing response to various forms of da...
One of the reasons that cancer is notoriously difficult to treat is that it can look very different for each patient. As a result, most targeted therapies only work for a fraction of cancer patients. ...
Stimulating the body’s immune system to attack tumors is a promising way to treat cancer. Scientists are working on two complementary strategies to achieve that: taking off the brakes that tumors put ...
Sachin Bhagchandani, a graduate student in the Department of Chemical Engineering currently working at the Koch Institute for Integrative Cancer Research, has won the National Cancer Institute Predoct...
Over the past decade, scientists have been exploring vaccination as a way to help fight cancer. These experimental cancer vaccines are designed to stimulate the body’s own immune system to destroy a t...
Pancreatic cancer, which affects about 60,000 Americans every year, is one of the deadliest forms of cancer. After diagnosis, fewer than 10 percent of patients survive for five years.
May 23, 2007,A James P. Wilmot Cancer Center scientist recently received two research grants, totaling more than $1.5 million, for separate, divergent studies of new therapies for follicular and mantl...
24 May 2007,William A. Wulf, the president of the U.S. National Academy of Engineering, tells a story about a successful inventor and entrepreneur who came to him recently and told him of developing a...
January 22, 2007,Autoimmune diseases such as type 1 diabetes, lupus and rheumatoid arthritis occur when the immune system fails to regulate itself. But researchers have not known precisely where the m...

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