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Engineers at MIT and the University of Massachusetts Medical School have designed a new type of nanoparticle that can be administered to the lungs, where it can deliver messenger RNA encoding useful p...
结核病(TB)是一种传染性疾病,也是全球范围内导致死亡的主要原因之一。结核分枝杆菌(MTB)是导致TB的细菌,据估计,2021年全球新发TB患者1060万人,并造成160万人死亡。近期,来自罗格斯大学与芝加哥大学等单位的研究团队,开发出一种新的基因组组装工具(Bact-Builder),并对MTB全球标准菌株H37Rv的参考基因组进行了全面更新。研究成果发表在《Nature Communicati...
Genetic engineering and personalized cell therapies could transform health care. In recent years, stem cells and gene-editing tools like CRISPR have been making headlines for the possibilities they of...
A seminal fluid protein transferred from male to female fruit flies during mating changes the expression of genes related to the fly’s circadian clock, an innovative technique has revealed.
tRNA作为核酸酶释放侧翼转录的识别位点,决定了哺乳动物线粒体中典型RNA加工过程,但并非所有的线粒体转录物都由tRNA控制。
捷克马萨里克大学中欧技术研究所的科研团队发现了一种新的细胞分化基因表达机制。该研究项目名为“植物减数分裂的调控及其操作技术的发展”,相关成果发表在《科学》上。
Sex differences in gene expression in alveolar type 2 (AT2) cells may underlie sex biases in the prevalence and severity of lung diseases, according to a study led by University of Pennsylvania scient...
From the tropics to the poles, from the sea surface to hundreds of feet below, the world’s oceans are teeming with one of the tiniest of organisms: a type of bacteria called Prochlorococcus, which des...
近日,联合国粮食及农业组织(FAO)发布主题为《基因编辑与农业食品系统》(Gene editing and agrifood systems)的议题报告(https://www.fao.org/3/cc3579en/cc3579en.pdf)。报告指出,在全球变暖、极端天气、水土退化、战争冲突、大流行病和人口变化的严重影响下,全球农业食品系统遭到了不同程度的破坏,由此导致了广泛的饥饿、营养不良和不...
Building on the CRISPR gene-editing system, MIT researchers have designed a new tool that can snip out faulty genes and replace them with new ones, in a safer and more efficient way.
It’s well-known that carrying one copy of the APOE4 gene variant increases one’s risk for Alzheimer’s disease threefold and two copies about tenfold, but the fundamental reasons why, and what can be d...
A team of scientists at the Whitehead Institute for Biomedical Research and the Broad Institute of MIT and Harvard has systematically evaluated the functions of over 5,000 essential human genes using ...
The liver’s ability to regenerate itself is legendary. Even if more than 70 percent of the organ is removed, the remaining tissue can regrow an entire new liver.
In recent years, scientists who study gene expression in cells have used a method that essentially pins a tail on RNA and tracks their whereabouts. However, certain types of RNA evade the process. Now...
Within a given tissue or organ, cells may appear very similar or even identical. But at the molecular level, these cells can have small differences that lead to wide variations in their functions.

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