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Computational Studies of the Structural Stability of Rabbit Prion Protein Compared to Human and Mouse Prion Proteins
Neurodegenerative Diseases Prion Diseases Immunity Rabbit Prion Protein Rabbit NMR X-ray and Homology Structures
2011/8/11
Abstract: Prion diseases are invariably fatal and highly infectious neurodegenerative diseases affecting humans and animals. The neurodegenerative diseases such as Creutzfeldt-Jakob disease, variant C...
Aptamer-Mediated Chemiluminescence Detection of Prion Protein on a Membrane Using Trimethoxyphenylglyoxal
Aptamer-Mediated Chemiluminescence Detection Prion Protein Membrane Using Trimethoxyphenylglyoxal
2010/9/13
Effective recognition and quantitative analysis of the prion protein are important in drug discovery and diagnosis for prion diseases, such as bovine spongiform encephalopathy and Creutzfeldt-Jakob di...
Regulation of Prion Protein Expression: A Potential Site for Therapeutic Intervention in the Transmissible Spongiform Encephalopathies
Prion Protein Expression Potential Site Therapeutic Intervention
2009/4/20
The Transmissible Spongiform Encephalopathies (TSEs) are a group of rare neurodegenerative diseases, which can be transmitted between members of the same species and possibly across different species....
Oxidative damage of prion protein induced by reactive oxygen species
Oxidative damage prion protein induced reactive oxygen species
2009/4/1
Prion protein (PrP) consists of an amino-terminal domain containing a series of octapeptide repeats with the consensus sequence PHGGGWGQ and a carboxyl-terminal domain composed of three α-helices and ...
The PCR-amplified prion protein (PrP) gene was sequenced to determine the frequency of scrapie-associated as well as novel PrP genotypes in 72 healthy goats representing five breeds. A total of six ge...
EXPRESSION OF CELLULAR ISOFORM OF PRION PROTEIN ON THE SURFACE OF PERIPHERAL BLOOD LYMPHOCYTES AMONG WOMEN EXPOSED TO LOW DOSES OF IONIZING RADIATION
radiation exposure cellular isoform of prion lymphocytes
2010/12/23
Ionizing radiation affects the expression of adhesive and co-stimulatory molecules in lymphocytes. The physiological function of cellular isoform of prion protein (PrPc) is little known.
专著信息
书名
Shao-man Yin, Man-Sun Sy, Po Tien*. An engineered PrPsc-like molecule from the chimera of mammalian prion protein and yeast prion-inducing domain. Acta Biochimica et Biophyica Sinica., 36 (2):...
专著信息
书名
Shao-man Yin, Yi Zheng, Po Tien. On-column purification and refolding of recombinant bovine prion protein: using its octarepeat sequences as a natural affinity tag. Protein Expression and Puri...
