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Robustness of an Odds-ratio Test in a Stratified Group Sequential Trial with a Binary Outcome Measure
Binary outcome Odds-ratio Stratification
2015/3/18
Many clinical trials compare two or more treatment groups by using a binary outcome measure.
For example, the goal could be to determine whether the frequency of pain episodes is
significantly reduc...
Estimation of the relative risk following group sequential procedure based upon the weighted log-rank statistic
Weighted Logrank Statistic Group Sequential Interim Analysis Estimation
2011/3/24
In this paper we consider a group sequentially monitored trial on a survival endpoint, monitored using a weighted log-rank (WLR) statistic with deterministic weight function. We introduce a summary st...
