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THE ROLE OF SMF 1, SMF-2, SMF-3 IN METAL-INDUCED WHOLE ANIMAL VULNERABILITY AND DOPAMINE NEURON DEGENERATION IN CAENORHABDITIS ELEGANS
dopamine C. elegans SMF aluminum copper Parkinson's Disease
2015/5/21
The etiology of many neurodegenerative diseases is unknown, but a number of studies indicate that a combination of both genetic and environmental factors contribute to the progression of disease. Expo...
Exposure to Oil during Meiosis Results in Alterations in Meiotic Chromosomes that are Similar to Age-Related Changes in the Nematode Caenorhabditis elegans
Oil Age Chromosome Synaptonemal Complex
2013/3/13
Exposure of young C. elegans nematodes to three different concentrations of oil resulted in changes in the meiotic chromosomes, nucleus, nucleolus, and nuclear envelope associations. Such alterations ...
蛋白激酶C在秀丽小杆线虫中具有调节肌细胞渐进性萎缩的功能.为了揭示它的调节机制, 本研究克隆了秀丽小杆线虫中蛋白激酶C pkc-2基因的cDNA pkc-2-c,构建了含该pkc-2基因cDNA亚型的重组质粒pPD 118.20-pKG 63;揭示了该cDNA在秀丽小杆线虫体壁肌细胞中的定位.
Evaluation of Caenorhabditis elegans as the Host in an Infection Model for Food-borne Pathogens
C. elegans Enteric pathogen Virulence
2009/4/8
The bacteriophagous nematode Caenorhabditis elegans has been recognized as a surrogate host for human pathogens. The aim of this study was to examine whether food-borne pathogens are pathogenic in nem...
Cathepsin L-like cysteine proteases from Brugia malayi:cDNA cloning and comparison with Caenorhabditis elegans
Cathepsin L-like cysteine proteases Brugia malayi cDNA cloning Caenorhabditis elegans
2009/3/3
Proteases are thought to be potentially useful targets for developing medicines to control filariasis caused by parasitic nematodes. To screen cysteine proteases essential for viability of nematodes...