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Narrowing the gap on heritability of common disease by direct estimation in case-control GWAS
Narrowing the gap heritability common disease direct estimation case-control GWAS
2013/6/17
One of the major developments in recent years in the search for missing heritability of human phenotypes is the adoption of linear mixed-effects models (LMMs) to estimate heritability due to genetic v...
A Direct Estimation Approach to Sparse Linear Discriminant Analysis
Classification constrained l1-minimization Fisher’s rule
2011/7/19
This paper considers sparse linear discriminant analysis of high-dimensional data. In contrast to the existing methods which are based on separate estimation of the precision matrix $\O$ and the diffe...