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ELUCIDATING MECHANISMS THAT LEAD TO PERSISTENT ANXIETY-LIKE BEHAVIOR IN RATS FOLLOWING REPEATED ACTIVATION OF CORTICOTROPIN-RELEASING FACTOR RECEPTORS IN THE BASOLATERAL AMYGDALA
anxiety corticotropin-releasing factor somatostatin amygdala basolateral amygdala
2015/5/21
Anxiety disorders are estimated to impact 1 in 4 individuals within their lifetime. For some individuals, repeated episodes of the stress response leads to pathological anxiety and depression. The str...
Vitamin C modulates oxidative stress-induced colitis in rats
Vitamin C colitis histopathology oxidative stress rats
2010/11/22
Free radicals are an important factor in the etiopathogenesis of colitis and may increase oxidative damage. The antioxidant vitamin C efficiently scavenges free oxygen radicals. The present study aime...
Electrolyzed-reduced water inhibits acute ethanol-induced hangovers in Sprague-Dawley rats
Electrolyzed-reduced ethanol-induced
2009/12/16
Ethanol consumption disturbs the balance between the pro- and anti-oxidant systems of the organism, leading to oxidative stress. Electrolyzed-reduced water (ERW) is widely used by people in East Asia ...
Administration of anti-glucagon-like peptide-2 serum suppresses epithelial cell proliferation of the distal small intestine in weanling rats
weanling rats cell proliferation
2009/12/16
We investigated the effects of endogenous glucagon-like peptide-2 (GLP-2) on the development of intestinal mucosa in weanling rats. Three-week-old male weanling Sprague-Dawley rats were administered e...
Effects of a dopamine receptor agonist and atropine sulfate on absorption of valproic acid in rats
dopamine receptor absorption valproic acid rats
2009/5/8
The aim of this study is to determine whether pramipexole hydrochloride hydrate (PHH) and atropine sulfate affect valproic acid (VPA) pharmacokinetics and to evaluate how plasma VPA concentrations a...
Efficacy of praziquantel (injection formula) in the treatment of Hymenolepis diminuta infection in laboratory rats by oral application
Praziquantel rat cestodes H. diminuta
2010/12/10
In this study, the efficacy of praziquantel (injection formula) by oral administration against Hymenolepis diminuta infection was evaluated in naturally infected rats. Forty-eight naturally infected r...