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In vivo and in vitro induction of cytochrome P-450 synthesis in hyperoxia
animal mice Cytochrome P-450 Dark Adaptation Light Adaptation
2009/7/17
Exposure of dark- or light-adapted mice to 1--3 ATA oxygen for times ranging from 15 min to 4 h caused a progressive increase in P-450, which peaked and then decayed. The rate of decay appears to be i...
Antidiuresis and inhibition of PGE2 excretion by hyperoxia in the conscious dog
Antidiuresis PGE2 hyperoxia Plasma antidiuretic hormone antagonism
2009/7/16
Experiments were performed to determine the influence of varying inspired oxygen tension on renal prostaglandin E2 (PGE2) excretion, renal hemodynamics, and water and electrolyte excretion in the cons...
Recent studies have documented a marked inhibition of renal prostaglandin E2 excretion during hyperbaric oxygenation (HBO) in the conscious dog. Numerous other studies have shown that pharmacological ...
Peripheral circulatory responses to acute hyperoxia
cardiovascular cardiac output animal dog
2009/7/15
Acute hyperoxia (1 atm) in anesthetized dogs produced a 14percent decrease in cardiac output relative to that observed with FIo2 = 0.21 and was associated with 7percent decreases in heart rate and str...
Synthesis of cytochrome P-450 in isolated liver cells during exposure to hyperoxia
animal mice cytochrome P-450 liver
2009/7/15
Mouse hepatocytes were separated within 15 min of the death of the animal. A method of determining cytochrome P-450 was developed and used to show that cells prepared quickly still contained normal le...
Blood-gas transport in awake rabbits exposed to normobaric hyperoxia
transport rabbits normobaric hyperoxia
2009/7/14
The time course and terminal effects of normobaric oxygen exposure on the gas transport chain were studied in awake, catheterized rabbits exposed to air (n = 8) for 96 h or 100percent O2 (n = 10) unti...
Effects of hyperoxia on human endothelial cell proliferation and morphology in vitro
human endothelial hyperoxia
2009/7/8
The effects of hyperoxia on endothelial cells from human umbilical veins were studied in vitro by flow cytometric DNA analysis, cell proliferation, and morphology. Exposure of the cells to PO2 of appr...
Hyperbaric hyperoxia enhances the lethal effects of amphotericin B in Leishmania braziliensis panamensis
hyperbaric human oxygen toxicity drug
2009/6/12
Leishmania braziliensis panamensis promastigotes were exposed in vitro to amphotericin B (AmB), menadione, or phenazine methosulfate under normoxic conditions. Promastigotes were also exposed to hyper...
Toxicity of hyperoxia and high pressure on C3H/10T1/2 cells and effects on cellular glutathione
animal mice pressure Toxicity
2009/6/8
Saturation diving involves the exposure of humans to elevated partial pressure of oxygen (PO2) and high ambient pressure. The present study is part of a research program that focuses on how such condi...
Glutathione in the cellular defense of human lung cells exposed to hyperoxia and high pressure
human oxygen toxicity high pressure
2009/6/8
Saturation diving involves exposure to elevated partial pressure of oxygen (Po2) and high pressure. The present work demonstrated that hyperoxic exposure for up to 72 h had significant effects on huma...
Exposure to hyperoxia in diving and hyperbaric medicine--effects on blood cell counts and serum ferritin
saturation hyperbaric blood cell count serum ferritin
2009/6/5
A reduction in hemoglobin concentration has been consistently reported after deep saturation dives, whereas reductions in thrombocyte counts and changes in biochemical parameters specific for liver fu...
Instantaneous beat-to-beat variability reflects vagal tone during hyperbaric hyperoxia
Diving Electrocardiography Ambulatory Hyperbaric Oxygenation Humans
2009/6/4
Hyperbaric hyperoxia affects heart rate variability (HRV) by increasing parasympathetic activity. The purpose of this study was to evaluate the applicability of instantaneous beat-to-beat variability ...
This presentation will focus on the effects of oxygen and some reactive chemical species
on interactions between circulating neutrophils and the vascular endothelium. It will also outline how we beli...
Superoxide dismutase responds to hyperoxia in rat hippocampus
Atmospheric Pressure Hippocampus enzymology Hyperbaric Oxygenation animal rat
2009/6/4
The brain's anti-oxidant response to highly elevated oxygen (O2) partial pressures is poorly understood. In this study we hypothesized that hyperbaric O2 (HBO2) would stimulate superoxide dismutase (S...
Reduced nitric oxide concentration in exhaled gas after exposure to hyperbaric hyperoxia
hyperbaric oxygenation nitric oxide exhaled breath condensate biochemical markers pulmonary oxygen toxicity Hydrogen Peroxide pulmonary function
2009/6/2
The objective of this study was to evaluate exhaled nitric oxide concentration (FENO) and exhaled breath condensate (EBC) pH and H2O2 as biochemical markers of pulmonary oxygen toxicity in association...
