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Colonoscopy has a central role in the detection and prevention of colorectal cancer. This is based on the fact that most colorectal cancer develops from premalignant adenomatous or serrated polyps, wh...
Familial cancer clinics strive to identify at-risk individuals with an inherited predisposition to cancer. Familial predisposition to colorectal cancer includes Familial Adenomatous Polyposis and Lync...
Colorectal cancer is the third most common type of cancer worldwide, with the highest incidences in Australia, New Zealand, Europe and North America, and the lowest in Africa and South-Central Asia. R...
Cyclooxygenase II:A Molecular Target for Colorectal Cancer Prevention and Treatment?
cyclooxygenase-2 (COX-2) microsomal prostaglandin E synthase-1 (mPGES-1) colorectal cancer chemoprevention COX-2 inhibitor
2009/7/15
PGE2 plays a key role in colon carcinogenesis. Evidence continues to accumulate that cyclooxygenase-2 (COX-2), an inducible COX isoform, represents a potential pharmacological target for the preventio...