搜索结果: 1-8 共查到“性科学 aromatase”相关记录8条 . 查询时间(0.082 秒)
Treatment of men with idiopathic oligozoospermic infertility using the aromatase inhibitor, testolactone. Results of a double-blinded, randomized, placebo-controlled trial with crossover
men idiopathic oligozoospermic infertility aromatase inhibitor testolactone
2009/2/23
The hypothesis that increased estradiol production may be the cause of impaired spermatogenesis in infertile men with idiopathic oligozoospermia was tested by administering the aromatase inhibitor...
Rat testicular germ cells and epididymal sperm contain active P450 aromatase
Estrogen testis epididymis
2009/2/17
Although testosterone is the principal sex steroid produced by the testis, estrogen is known to be produced by both Leydig and Sertoli cells during different developmental periods. Additionally, evide...
P450 aromatase messenger ribonucleic acid expression in male rat germ cells: detection by reverse transcription-polymerase chain reaction amplification
Germ cells spermatids P450 aromatase estrogen
2009/2/17
We have previously demonstrated that cytochrome P450 aromatase (P450arom) protein, an estrogen-synthesizing enzyme, is present and active in germ cells of the adult mouse testis. To establish that P...
Mouse epididymal sperm contain active P450 aromatase which decreases as sperm traverse the epididymis
Spermatozoa estrogen efferent ductules cytoplasmic droplet testicular excurrent ducts
2009/2/16
Recently we reported that mouse germ cells in the testis contain active P450 aromatase (P450arom), the enzyme that converts androgens to estrogens. This finding suggested that germ cells have the ...
Anti-androgen effects of the aromatase inhibitor, atamestane
Anti-androgen effects aromatase inhibitor atamestane
2009/2/13
Prostatic hyperplasia can be induced in both intact and castrated dogs and in intact cynomolgus monkeys by the administration of androgenic steroids. Estrogenic steroids potentiate this effect in ...
Atamestane, a new aromatase inhibitor for the management of benign prostatic hyperplasia
aromatase inhibitor management benign prostatic hyperplasia
2009/2/7
Atamestane is a new, competitive, and irreversible inhibitor of estrogen biosynthesis. Its pharmacologic action has been evaluated in mice, rats, rabbits, dogs, monkeys, and humans. In rats, atame...
Rationale for using aromatase inhibitors to manage benign prostatic hyperplasia. Experimental studies
aromatase inhibitors prostatic hyperplasia Experimental studies
2009/2/7
Today, human benign prostatic hyperplasia (BPH) is considered primarily to be a disease of the stroma, in which estrogens are thought to play a considerable causative or permissive role. The growi...
Characterization of the fertility of male aromatase knockout mice
Estrogen spermatogenesis sexual behavior
2008/12/29
Previous studies employing the male aromatase knockout (ArKO) mouse have indicated that local expression of estrogens appears to be important for the progression of spermatogenesis. In the absence o...
