搜索结果: 1-11 共查到“口腔医学 BMP-2”相关记录11条 . 查询时间(0.057 秒)
目的:通过建立兔子牙移动的模型,研究三七总皂苷(panax notoginseng saponin,PNS)对正牙过程中牙槽骨改建及牙周组织中BMP-2表达的影响。方法:选取32只3~6月龄的新西兰白兔随机分成PNS组和生理盐水(normal saline,NS)组,通过肌肉注射血栓通[40 mg/kg·d-1]和NS。每组各16只,又分为7、14、21、28 d 4个亚组,分别于正畸牙移动1周、...
Ad-BMP-2基因转移诱导兔下颌骨骨膜成骨的实验研究
基因治疗 骨形态发生蛋白2 骨膜 骨形成
2012/7/2
探讨腺病毒介导的骨形态发生蛋白2（Ad-BMP-2）局部基因转移对兔下颌升支外侧骨膜处异位成骨的诱导作用。方法 选用18只成年新西兰大白兔作为实验动物，在一侧下颌升支外侧骨膜处注射0.2mL Ad-BMP-2(共含病毒滴度2×109pfu)为实验组,对侧注射等量的PBS为对照组，术后2、5、10周分别处死6只动物，行大体观察、影像学和组织学检查，观察新骨形成的时间和空间变化特点。结果 Ad-B...
Localization of Bmp-4, Shh and Wnt-5a transcripts during early mice tooth development by in situ hybridization
Odontogenesis Tooth germ Wnt proteins Bone morphogenetic proteins
2009/10/19
A comparative nonisotopic in situ hybridization (ISH) analysis was carried out for the detection of Bmp-4, Shh and Wnt-5a transcripts during mice odontogenesis from initiation to cap stage. Bmp-4 was ...
Effects of Dose of Recombinant Human BMP-2 on Bone Formation at Palatal Sites in Young and Old Rats
Dose of rhBMP-2 Bone formation Aging
2009/9/14
This study was designed to examine the effects of dose of recombinant human BMP-2 (rhBMP-2) on bone formation at palatal sites in 10-week-old (10w) and 70-week-old (70w) rats, when combined with a pol...
Periodontal Regeneration by BMP-2 Application to Root Dentin Surface
BMP-2 periodontal regeneration cementum formation ankylosis
2009/5/27
The objective of this study was to evaluate periodontal regeneration in canine premolars after application of bone morphogenetic protein (BMP)-2 to root dentin surfaces.
Eighty periodontal defects us...
Induction of TGF-β and BMP-2 by Simvastatin in Human Periodontal Ligament Cells
simvastatin human periodontal ligament (HPDL) cells transforming growth factor-β1 (TGF-β1) bone morphogenetic protein-2 (BMP-2)
2009/5/21
Statins, which are highly effective cholesterol-lowering drugs, induce bone morphogenetic protein (BMP)-2 expression. However, the other growth factors except for BMP-2 and the effects of statins on p...
Suppression of cementum-like tissue formation on BMP-2-applied dentin surface by bisphosphonate
rhBMP-2 dentin resorption cementum-like tissue bisphosphonate
2009/5/20
We studied the effects of bisphosphonate administration on cementum-like tissue formation and dentin resorption induced by BMP-2 in rats.
Incadronate (1μg/kg/day) was administered intraperitoneally t...
Periodontal regeneration by BMP-2 solution and collagen hydrogel application to root dentin surface
BMP-2 collagen hydrogel periodontal regeneration
2009/5/20
We evaluates periodontal regeneration in a dehiscence model after the application of BMP-2 solution and collagen hydrogel to the root dentin surface.
Materials were 128 premolars of 8 beagles. After ...
Effect of BMP-2 application to root dentin surface on periodontal regeneration in 1-wall infrabony defects
BMP-2 periodontal regeneration 1-wall infrabony defects
2009/5/15
This study evaluated periodontal regeneration after the application of BMP-2 to root dentin surface in 1-wall infrabony defects.The mandibular first and third premolars in seven beagle dogs were extra...
BMP-2,3,4,5在颌面部神经鞘瘤中的表达分析
BMP 神经鞘瘤 恶性 原位杂交
2010/8/20
目的:探讨BMPs 家族成员与外周神经肿瘤的关系。方法:用原位杂交方法对BMP22 ,3 ,4 ,5 在人良、恶性神经鞘瘤中的表达进行观察。结果:显示BMP22 ,3 ,4 ,5 mRNA在外周神经的良恶性神经鞘瘤中均有分布。良性肿瘤中,呈栅栏状排列,肿瘤细胞聚集的区域BMPs 表达升高;恶性肿瘤中BMPs 的表达高于良性肿瘤。结论:确定了BMPs 在外周神经肿瘤中的表达和分布,揭示部分BMPs ...
多形性腺瘤中BMP的表达及作用机制分析
骨形成蛋白 多形性腺瘤 反转录聚合酶链式反应
2010/9/8
目的:检测多形性腺瘤中BMP 蛋白的表达及BMP2 mRNA 的扩增情况,以探讨多形性腺瘤的病理发生机制。方法:应用BMP 的单克隆抗体检测BMP 在多形性腺瘤中的表达,并进一步应用BMP2 的特异性引物和RT2PCR 的方法,扩增6 例多形性腺瘤组织中的RNA。结果: 6 例多形性腺瘤组织中可以检测到BMP 蛋白的扩增,其中5 例有BMP2 mRNA 的扩增。结论:BMP 可能参与了多形性腺瘤的...