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Lipocalin-Type Prostaglandin D Synthase and Egg White Cystatin React with IgE Antibodies from Children with Egg Allergy
cystatin food allergy hen's egg white LC-MS/MS lipocalin-type prostaglandin D synthase
2010/11/12
Background: Ovalbumin, ovomucoid, ovotransferrin, lysozyme, and ovomucin are known to be major allergens found in egg white. Egg white protein is composed of over 30 proteins; many of which have neith...
Allergy to Salsola Kali in a Salsola Incanescens-rich Area: Role of Extensive Cross Allergenicity
cross allergenisity Salsola incanescens Salsola Kali
2010/11/16
Background: Pollens from the Salsola spp. are an important source of respiratory allergy in tropical countries. Our aim was to characterize the IgE binding proteins of S. incanescens pollen extract an...
Sho-seiryu-to Suppresses Histamine Signaling at the Transcriptional Level in TDI-Sensitized Nasal Allergy Model Rats
allergy gene expression histamine H1 receptors histamine signaling histidine decarboxylase Th2 cytokines
2010/11/16
SST significantly suppressed TDI-induced nasal allergy-like symptoms. TDI provocation showed a significant up-regulation of histamine H1 receptor (H1R) and histidine decarboxylase (HDC) gene expressio...
Analysis of Helper T Cell Responses to Cry j 1-Derived Peptides in Patients with Nasal Allergy: Candidate for Peptide-Based Immunotherapy of Japanese Cedar Pollinosis
Cry j 1 immunotherapy nasal allergy peptide Th response
2010/11/16
Our results suggest four Cry j 1-derived peptides (p61-80, p115-132, p206-225 and p337-353) may be considered to be the immunodominant T-cell epitopes of the Cry j 1 molecule, and can be useful for th...
Dendritic Cells—Importance in Allergy—
asthma atopic dermatitis contact dermatitis Th1/Th2
2010/11/18
In this review we discuss the role of dendritic cells (DC) in the pathogenesis of allergic contact hypersensitivity (ACH) and atopic disorders, such as asthma and atopic eczema. In ACH patients, DC re...
No Association of Polymorphisms in the 5' Region of the CD14 Gene and Food Allergy in a Japanese Population
5' region CD14 food allergy gene polymorphism
2010/11/18
Background: The gene encoding CD14 is a positional candidate gene for allergic diseases as it is localized on chromosome 5q31, a region that is linked to atopy-related phenotypes.
Although it has bee...
Specific IgE to recombinant allergens (rBetv1 and rBetv2) and apple allergy in patients with pollinosis
apple oral allergy syndrome rBetv1 rBetv2
2010/11/29
The presence of IgE antibodies to the allergens rBetv1 and rBetv2 was investigated in the sera of 99 patients with specific IgE to apple extract by comparing a group of 43 patients who had oral allerg...
Immune Mechanisms in Drug Allergy
autologous cytotoxicity drug hypersensitivity epidermal HLA immunologic T-lymphocytes toxic
2010/11/18
In the last decade several teams of researchers obtained in vitro drug-specific human T-cell clones, in a variety of clinical types of drug eruptions. These clones were produced from blood or skin mon...
Immunological adjuvants in allergy vaccines: Past, present and future
adjuvant allergy aluminum salts immunotherapy monophosphoryl lipid A T helper 1 cells T helper 2 cells
2010/11/25
Hundreds of compounds have been tested over the years in a search for adjuvants to incorporate with antigens or allergens to enhance the immune response. Despite this, aluminum salts have been the onl...
Translation of the human genome into clinical allergy, part 2
basophils mast cells microarray system biology transcriptome
2010/11/22
After completion of sequencing of the human genome, you will no longer be able to discover a new gene and may not be able to find a new molecule in the human body. Instead, you may find many new molec...
Latex allergy in a dental nurse: Late nasal response is associated with eosinophil recruitment and T helper 2 cell type cytokine mRNA expression
eosinophils late nasal responses latex allergy T cells Th2 type cytokine
2010/11/29
The occupational uses of latex gloves may be associated with allergic rhinitis. Hypersensitivity to latex has been shown to be IgE-mediated. However, late nasal responses to latex have not been report...